Evidence map›Paper›PMID 30925701›Full record

ArticleInternational journal of molecular sciences2019

Comprehensive Genomic Profiling of Androgen-Receptor-Negative Canine Prostate Cancer.

Renée Laufer-Amorim, Carlos Eduardo Fonseca-Alves, Rolando Andre Rios Villacis, Sandra Aparecida Drigo Linde, Marcio Carvalho, Simon Jonas Larsen, Fabio Albuquerque Marchi, Silvia Regina Rogatto

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Review of Molecular Technologies for Investigating Canine Cancer.Animals : an open access journal from MDPI · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Open veterinary journal · 2023
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Effects of the Latex ofFrontiers in veterinary science · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Renée Laufer-AmorimDepartment of Veterinary Clinic, School of Veterinary Medicine and Animal Science, São Paulo State University-UNESP, Botucatu 18680-970, Brazil. renee.laufer-amorim@unesp.br.
Carlos Eduardo Fonseca-AlvesDepartment of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, São Paulo State University-UNESP, Botucatu 18680-970, Brazil. carlos.e.alves@unesp.br.ORCID 0000-0002-6702-6139
Rolando Andre Rios VillacisDepartment of Genetics and Morphology, Institute of Biological Sciences, University of Brasília-UnB, Brasília 70910-900, Brazil. andrevillacis@yahoo.com.br.
Sandra Aparecida Drigo LindeDepartment of Veterinary Clinic, School of Veterinary Medicine and Animal Science, São Paulo State University-UNESP, Botucatu 18680-970, Brazil. sandradrigo@gmail.com.ORCID 0000-0001-6747-6642
Marcio CarvalhoDepartment of Veterinary Clinic, School of Veterinary Medicine and Animal Science, São Paulo State University-UNESP, Botucatu 18680-970, Brazil. marcio.carvalho@unesp.br.
Simon Jonas LarsenDepartment of Mathematics and Computer Science, University of Southern Denmark, 5230 Odense, Denmark. sjlarsen@imada.sdu.dk.ORCID 0000-0001-8076-5035
Fabio Albuquerque MarchiInternational Research Center (CIPE), A.C. Camargo Cancer Center, São Paulo 01508-010, Brazil. fabio.marchi@accamargo.org.br.ORCID 0000-0001-5815-8423
Silvia Regina RogattoDepartment of Clinical Genetics, Vejle Hospital, Institute of Regional Health Research, University of Southern Denmark, 7100 Vejle, Denmark. silvia.regina.rogatto@rsyd.dk.
Universidade Estadual Paulista (Unesp) · BRUniversity of Southern Denmark · DKAC Camargo Hospital · BRUniversidade de Brasília · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2008/57221-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2015/25400-7
6 · The paper itself

Abstract

Canine carcinomas have been considered natural models for human diseases; however, the genomic profile of canine prostate cancers (PCs) has not been explored. In this study, 14 PC androgen-receptor-negative cases, 4 proliferative inflammatory atrophies (PIA), and 5 normal prostate tissues were investigated by array-based comparative genomic hybridization (aCGH). Copy number alterations (CNAs) were assessed using the Canine Genome CGH Microarray 4 × 44K (Agilent Technologies). Genes covered by recurrent CNAs were submitted to enrichment and cross-validation analysis. In addition, the expression levels of

Indexed as

Gene Expression Regulation, NeoplasticTranscriptomeAnimalsComparative Genomic HybridizationDNA Copy Number VariationsDog DiseasesDogsGenomic InstabilityGenomicsMaleProstatic NeoplasmsProto-Oncogene Proteins c-mdm2Receptors, AndrogenTumor Suppressor Protein p53Proto-Oncogene Proteins c-mdm2Receptors, AndrogenTumor Suppressor Protein p53comparative oncologycopy number alterationdogmicroarrayproliferative inflammatory atrophyprostate cancer

Identifiers

PMID30925701
PMCPMC6480132
OpenAlexW2923768462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.