Evidence map›Paper›PMID 30925334›Full record

SynthesisJournal of anxiety disorders2019

Early interventions to prevent posttraumatic stress disorder symptoms in survivors of life-threatening medical events: A systematic review.

Jeffrey L Birk, Jennifer A Sumner, Mytra Haerizadeh, Reuben Heyman-Kantor, Louise Falzon, Christopher Gonzalez, Liliya Gershengoren, Peter Shapiro, Donald Edmondson, Ian M Kronish

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Journal of anxiety disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Psychological and behavioral dimensions in cardiac arrest survivors and their families: A state-of-the-art review.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  8. Clinical Education: Addressing Prior Trauma and Its Impacts in Medical Settings.Journal of clinical psychology in medical settings · 2024
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Four-symptom model of medical-related posttraumatic stress among adult cancer patients.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2022
    Article
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jeffrey L BirkCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, 622 West 168(th) Street, New York, NY, 10032, USA.
Jennifer A SumnerCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, 622 West 168(th) Street, New York, NY, 10032, USA.
Mytra HaerizadehCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, 622 West 168(th) Street, New York, NY, 10032, USA.
Reuben Heyman-KantorCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, 622 West 168(th) Street, New York, NY, 10032, USA.
Louise FalzonCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, 622 West 168(th) Street, New York, NY, 10032, USA.
Christopher GonzalezCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, 622 West 168(th) Street, New York, NY, 10032, USA.
Liliya GershengorenDepartment of Psychiatry, Weill Cornell Medical Center, 525 East 68(th) Street, New York, NY, 10065, USA.
Peter ShapiroDepartment of Psychiatry, Columbia University Medical Center, 622 West 168(th) Street, New York, NY, 10032, USA.
Donald EdmondsonCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, 622 West 168(th) Street, New York, NY, 10032, USA.
Ian M KronishCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, 622 West 168(th) Street, New York, NY, 10032, USA. Electronic address: ik2293@cumc.columbia.edu.
Columbia University Irving Medical Center · USCornell University · US

Funding

Impact of Social-Interpersonal Factors in the ER on PTSD/Cardiac OutcomesR01HL117832 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DAVIDSON, KARINA W., EDMONDSON, DONALD · 2013 to 2017
$3.1M
Impact of PTSD on cardiovascular risk in survivors of stroke and transient ischemic attackR01HL132347 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI EDMONDSON, DONALD, KRONISH, IAN MATTHEW · 2016 to 2019
$3.1M
PTSD, Medication Adherence, and Prognosis after Acute Coronary SyndromesR01HL123368 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DAVIDSON, KARINA W., KRONISH, IAN MATTHEW · 2014 to 2017
$1.6M
Posttraumatic Stress and Cardiovascular Risk in Women: Tests of Biological MechanismsK01HL130650 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SUMNER, JENNIFER A · 2016 to 2020
$815k
Investigating fear of recurrence as a modifiable mechanism of behavior change to improve medication adherence in acute coronary syndrome patientsR21HL145970 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BIRK, JEFFREY LEE · 2018 to 2019
$446k
NHLBI NIH HHS K01 HL130650NHLBI NIH HHS R01 HL117832NHLBI NIH HHS R01 HL123368NHLBI NIH HHS R01 HL132347NHLBI NIH HHS R21 HL145970
6 · The paper itself

Abstract

Post-traumatic stress disorder (PTSD) induced by life-threatening medical events has been associated with adverse physical and mental health outcomes, but it is unclear whether early interventions to prevent the onset of PTSD after these events are efficacious. We conducted a systematic review to address this need. We searched six biomedical electronic databases from database inception to October 2018. Eligible studies used randomized designs, evaluated interventions initiated within 3 months of potentially traumatic medical events, included adult participants, and did not have high risk of bias. The 21 included studies (N = 4,486) assessed a heterogeneous set of interventions after critical illness (9), cancer diagnosis (8), heart disease (2), and cardiopulmonary surgery (2). Fourteen psychological, 2 pharmacological, and 5 other-type interventions were assessed. Four of the psychological interventions emphasizing cognitive behavioral therapy or meaning-making, 1 other-type palliative care intervention, and 1 pharmacological-only intervention (hydrocortisone administration) were efficacious at reducing PTSD symptoms relative to control. One early, in-hospital counseling intervention was less efficacious at lowering PTSD symptoms than an active control. Clinical and methodological heterogeneity prevented quantitative pooling of data. While several promising interventions were identified, strong evidence of efficacy for any specific early PTSD intervention after medical events is currently lacking.

Indexed as

Cognitive Behavioral TherapyEarly Medical InterventionCardiopulmonary BypassCritical IllnessHeart DiseasesHumansHydrocortisoneNeoplasmsStress Disorders, Post-TraumaticSurvivorsHydrocortisoneInterventionMedical eventsPosttraumatic stress disorder (PTSD)PreventionSystematic review

Identifiers

PMID30925334
PMCPMC6504609
OpenAlexW2924264124

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.