ArticleInvestigative ophthalmology & visual science2019
Macula Vessel Density and Foveal Avascular Zone Parameters in Exfoliation Glaucoma Compared to Primary Open-Angle Glaucoma.
Article in Investigative ophthalmology & visual science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- A Novel CRYBB2 Splicing Mutation Is Associated With Lens Extracellular Matrix Remodeling and Vascular Alterations in Congenital Cataract.Investigative ophthalmology & visual science · 2026Article
- The AROMA Dataset for Automatic Detection of Artifact Type and Severity in Retinal Optical Coherence Tomography Angiography.Ophthalmic research · 2026Article
- Swept-Source Optical Coherence Tomography Angiography for Retinal Neurovascular Structural Evaluation in a Chronic Unpredictable Mild Stress Rat Model.Translational vision science & technology · 2025Article
- Comparing structural and vascular parameters between advanced pseudoexfoliation glaucoma and primary open angle glaucoma using optical coherence tomography angiography.BMC ophthalmology · 2025Article
- SUPERFICIAL VESSEL DENSITY, RETINAL NERVE FIBER LAYER THICKNESS, AND VISUAL FIELD LOSS IN PRIMARY OPEN-ANGLE AND PSEUDOEXFOLIATIVE GLAUCOMA.Acta clinica Croatica · 2024Article
- Enhancing foveal avascular zone analysis for Alzheimer's diagnosis with AI segmentation and machine learning using multiple radiomic features.Scientific reports · 2024Article
- Applications of optical coherence tomography angiography in glaucoma: current status and future directions.Frontiers in medicine · 2024Review
- Peripapillary and fovea avascular zone optical coherence tomography angiography parameters in exfoliation glaucoma versus primary open-angle glaucoma versus healthy eyes.Indian journal of ophthalmology · 2022Article
- Optical Coherence Tomography Angiography Findings in Primary Open-Angle and Pseudoexfoliation Glaucoma.Turkish journal of ophthalmology · 2022Article
- The Role of Vessel Density as Measured by Optical Coherence Tomography Angiography in the Evaluation of Pseudoexfoliative Glaucoma: A Review of the Literature.Ophthalmology and therapy · 2022Review
- Optical Coherence Tomography and Glaucoma.Annual review of vision science · 2021Review
- Comparison of vessel density in macular and peripapillary regions between primary open-angle glaucoma and pseudoexfoliation glaucoma using OCTA.International ophthalmology · 2021Article
- Cut-Off Values of Foveal Vascular Indices in Exfoliation Glaucoma.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Magnitude of Diurnal Change in Retinal Vessel Density: Comparison Between Exfoliative Glaucoma and Primary Open-Angle Glaucoma.Beyoglu eye journal · 2021Article
- Macular vessel density and foveal avascular zone parameters in patients after acute primary angle closure determined by OCT angiography.Scientific reports · 2020Article
- Quantitative analysis of radial peripapillary capillary plexuses in patients with clinically unilateral pseudoexfoliation syndrome.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Article
- Optical Coherence Tomography Angiography in Glaucoma.Journal of glaucoma · 2020Review
- Quantitative optical coherence tomography angiography: A review.Experimental biology and medicine (Maywood, N.J.) · 2020Review
- Peripapillary perfused capillary density in true versus pseudoexfoliation syndrome: An OCTA study.PloS one · 2020Article
- Optical coherence tomography angiography of the peripapillary region and macula in normal, primary open angle glaucoma, pseudoexfoliation glaucoma and ocular hypertension eyes.International journal of ophthalmology · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Purpose: The purpose of this study was to explore macula vessel density and foveal avascular zone (FAZ) parameters in exfoliation glaucoma (XFG) compared to primary open-angle glaucoma (POAG) using optical coherence tomography angiography (OCTA). Methods: This was a cross-sectional observational study. Twenty-six XFG and 28 POAG patients with comparable visual field defects on Humphrey 24-2 and 10-2 perimetries were recruited. OCTA scans (3 × 3 mm) centered on the fovea were obtained. Built-in software was used to measure superficial capillary plexus (SCP) vessel density at different quadrants of the macula. Custom software was then used to create a full-thickness image. The FAZ was manually delineated, and large vessels were removed. Vessel density in eight concentric rings with increments of 200-μm diameters from the delineated FAZ was measured. FAZ parameters were calculated using the custom software. Results: SCP density was significantly lower in the superior (mean difference [MD] = -4.32, 95% confidence interval [CI] = -7.02, -1.61, P = 0.003) and nasal (MD = -3.00, 95% CI = 05.22, -0.77, P = 0.010) quadrants in XFG versus POAG. SCP vessel density using the concentric ring approach revealed significantly decreased values at all eight rings in XFG versus POAG. In the full-thickness analysis, density was significantly less in the XFG group in all rings except the initial 200 μm. No significant differences existed in FAZ parameters between the groups. Conclusions: Despite the presence of comparable central visual field defects, the macula vessel density was predominately lower in XFG compared with POAG in our sample of patients. Further studies are warranted to investigate the consistency of our results.
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