ArticleNMR in biomedicine2019
Reproducibility of human cardiac phosphorus MRS (
Article in NMR in biomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Repeatability of Rapid Human Cardiac Phosphorus MRSI (Magnetic resonance in medicine · 2026Article
- Article
- Imaging of metabolic dysfunction in genetic cardiomyopathies.The international journal of cardiovascular imaging · 2025Review
- Regionally resolved cardiac metabolism using a dipole-loop array coil for 7 TMagnetic resonance in medicine · 2025Article
- Feasibility and comparison of 3D modified rosette ultra-short echo time (PETALUTE) with conventional weighted acquisition inScientific reports · 2025Article
- 3D ultra-short echo timeResearch square · 2024Article
- 17β-Estradiol Effects in Skeletal Muscle: ADiagnostics (Basel, Switzerland) · 2024Article
- Compartment-based reconstruction of 3D acquisition-weightedNMR in biomedicine · 2023Article
- Radiofrequency antenna concepts for human cardiac MR at 14.0 T.Magma (New York, N.Y.) · 2023Article
- CardiacHeart failure reviews · 2023Review
- Ultra-high field cardiac MRI in large animals and humans for translational cardiovascular research.Frontiers in cardiovascular medicine · 2023Article
- Three-dimensional, 2.5-minute, 7T phosphorus magnetic resonance spectroscopic imaging of the human heart using concentric rings.NMR in biomedicine · 2023Article
- Compartment-based reconstruction of acquisition-weightedFrontiers in physiology · 2023Article
- Magnetic resonance imaging of cardiac metabolism in heart failure: how far have we come?European heart journal. Cardiovascular Imaging · 2022Article
- Coexistent Diabetes Is Associated With the Presence of Adverse Phenotypic Features in Patients With Hypertrophic Cardiomyopathy.Diabetes care · 2022Article
- In Vivo Magnetic Resonance Spectroscopy Methods for Investigating Cardiac Metabolism.Metabolites · 2022Review
- Evaluation of Acute Supplementation With the Ketone Ester (Frontiers in physiology · 2022Article
- Increased cardiac Pi/PCr in the diabetic heart observed using phosphorus magnetic resonance spectroscopy at 7T.PloS one · 2022Article
- PCA denoising and Wiener deconvolution ofMagnetic resonance in medicine · 2021Article
- Investigating the effect of trigger delay on cardiac 31P MRS signals.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
purposeWe test the reproducibility of human cardiac phosphorus MRS (
methods10 healthy subjects were scanned on two occasions: one to test the 28 min 3D-CSI protocol, and one to test the 6½ min protocol. Spectra were fitted using the OXSA MATLAB toolbox. The phosphocreatine to adenosine triphosphate concentration ratio (PCr/ATP) from each scan was analysed for intra- and intersubject variability. The impact of different strategies for voxel selection was assessed.
resultsThere were no significant differences between repeated measurements in the same subject. For the 28 min protocol, PCr/ATP in the midseptal voxel across all scans was 1.91 ± 0.36 (mean ± intersubject SD). For the 6½ min protocol, PCr/ATP in the midseptal voxel was 1.76 ± 0.40. The coefficients of reproducibility (CRs) were 0.49 (28 min) and 0.67 (6½ min). Per-subject B
conclusionsBoth 7 T protocols show improved reproducibility compared with a previous 3 T study by Tyler et al. Our results will enable informed power calculations and protocol selection for future clinical research studies.
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