Evidence map›Paper›PMID 30924538›Full record

ArticleThe Medical journal of Australia2019

Updated Australian consensus statement on management of inherited bleeding disorders in pregnancy.

Scott Dunkley, Julie A Curtin, Anthony J Marren, Robert P Heavener, Simon McRae, Jennifer L Curnow

Open access · hybridAbstract readConsensus Statement
In one paragraph

Article in The Medical journal of Australia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. von Willebrand disease: an illustrated review.Research and practice in thrombosis and haemostasis · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Scott DunkleyInstitute of Haematology, Royal Prince Alfred Hospital, Sydney, NSW.
Julie A CurtinThe Children's Hospital at Westmead, Sydney, NSW.
Anthony J MarrenRoyal Prince Alfred Hospital, Sydney, NSW.
Robert P HeavenerRoyal Prince Alfred Hospital, Sydney, NSW.
Simon McRaeRoyal Adelaide Hospital, Adelaide, SA.
Jennifer L CurnowHaemophilia Treatment Centre, Westmead Hospital, Sydney, NSW.
Royal Prince Alfred Hospital · AUChildren's Hospital at Westmead · AURoyal Adelaide Hospital · AUWestmead Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere have been significant advances in the understanding of the management of inherited bleeding disorders in pregnancy since the last Australian Haemophilia Centre Directors' Organisation (AHCDO) consensus statement was published in 2009. This updated consensus statement provides practical information for clinicians managing pregnant women who have, or carry a gene for, inherited bleeding disorders, and their potentially affected infants. It represents the consensus opinion of all AHCDO members; where evidence was lacking, recommendations have been based on clinical experience and consensus opinion. MAIN RECOMMENDATIONS: During pregnancy and delivery, women with inherited bleeding disorders may be exposed to haemostatic challenges. Women with inherited bleeding disorders, and their potentially affected infants, need specialised care during pregnancy, delivery, and postpartum, and should be managed by a multidisciplinary team that includes at a minimum an obstetrician, anaesthetist, paediatrician or neonatologist, and haematologist. Recommendations on management of pregnancy, labour, delivery, obstetric anaesthesia and postpartum care, including reducing and treating postpartum haemorrhage, are included. The management of infants known to have or be at risk of an inherited bleeding disorder is also covered. CHANGES IN MANAGEMENT AS A RESULT OF THIS STATEMENT: Key changes in this update include the addition of a summary of the expected physiological changes in coagulation factors and phenotypic severity of bleeding disorders in pregnancy; a flow chart for the recommended clinical management during pregnancy and delivery; guidance for the use of regional anaesthetic; and prophylactic treatment recommendations including concomitant tranexamic acid.

Indexed as

Anesthesia, ObstetricalAustraliaBlood Coagulation Disorders, InheritedBlood Coagulation FactorsFemaleHemostaticsHumansInfant, NewbornPatient Care TeamPostpartum HemorrhagePregnancyPregnancy Complications, HematologicSocieties, MedicalBlood Coagulation FactorsHemostaticsBlood platelet disordersCoagulation disordersGenetic counselingPostpartumPregnancyPrenatal diagnosisTransfusion medicine

Identifiers

PMID30924538
PMCPMC6850504
OpenAlexW2933216078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.