Evidence map›Paper›PMID 30924468›Full record

ArticleChemical communications (Cambridge, England)2019

Synthetic and immunological studies of Salmonella Enteritidis O-antigen tetrasaccharides as potential anti-Salmonella vaccines.

Chang-Xin Huo, Debashis Dhara, Scott M Baliban, Setare Tahmasebi Nick, Zibin Tan, Raphael Simon, Anup Kumar Misra, Xuefei Huang

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Synthesis ofThe Journal of organic chemistry · 2024
    Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Total synthesis of the O-antigen repeating unit ofBeilstein journal of organic chemistry · 2021
    Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chang-Xin HuoDepartments of Chemistry and Biomedical Engineering, Institute for Quantitative Health Science & Engineering, Michigan State University, 578 South Shaw Lane, East Lansing, MI 48824, USA. xuefei@chemistry.msu.edu.
Debashis Dhara
Scott M Baliban
Setare Tahmasebi Nick
Zibin Tan
Raphael Simon
Anup Kumar Misra
Xuefei Huang

Funding

FELLOWSHIP TRAINING PROGRAM IN VACCINOLOGYT32AI007524 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Marcelo B. Sztein · 1997 to 2026
$6.4M
Generation of active immunity against cytotoxic oligomeric tau speciesR01CA225105 · NCI · MICHIGAN STATE UNIVERSITY · PI HUANG, XUEFEI · 2018 to 2023
$2.8M
Virus like particles as carriers for carbohydrate based anti-Salmonella vaccinesR03AI111054 · NIAID · MICHIGAN STATE UNIVERSITY · PI HUANG, XUEFEI · 2015 to 2016
$154k
NCI NIH HHS R01 CA225105NIAID NIH HHS R03 AI111054NIAID NIH HHS T32 AI007524
6 · The paper itself

Abstract

The first synthetic carbohydrate based potential anti-Salmonella Enteritidis vaccine has been developed by conjugating a synthetic tetrasaccharide antigen with bacteriophage Qβ. High levels of specific and long lasting anti-glycan IgG antibodies were induced by the conjugate, which completely protected mice from lethal bacterial challenges in a passive transfer model.

Indexed as

AllolevivirusAnimalsAntibodies, BacterialImmunoglobulin GMiceO AntigensOligosaccharidesSalmonella enteritidisSalmonella Infections, AnimalSalmonella VaccinesSurvival RateVaccines, Virus-Like ParticleAntibodies, BacterialImmunoglobulin GO AntigensOligosaccharidesSalmonella VaccinesVaccines, Virus-Like Particle

Identifiers

PMID30924468
PMCPMC6525565

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.