Evidence map›Paper›PMID 30924413›Full record

Trial reportWomen's health (London, England)

Home ovulation test use and stress during subfertility evaluation: Subarm of a randomized controlled trial.

Sarah Weddell, Georgina L Jones, Sheila Duffy, Cameron Hogg, Sarah Johnson, William Ledger

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Women's health (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06127875 (Effects of Trying to Conceive Using an Home- or Hospital-based Ovulation Monitoring on Stress), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06127875 completednot on this map

Effects of Trying to Conceive Using an Home- or Hospital-based Ovulation Monitoring on Stress

TypeobservationalSponsorThe First Hospital of Jilin UniversityRan2023 to 2024Enrolled311ConditionsFertility Issues, Stress, Psychological
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarah Weddell1 Scientific and Medical Affairs, SPD Swiss Precision Diagnostics Development Company Limited, Bedford, UK.
Georgina L Jones2 Department of Psychology, School of Social Sciences, Leeds Beckett University, Leeds, UK.
Sheila Duffy3 Department of Obstetrics and Gynaecology, Royal Hallamshire Hospital, Sheffield, UK.
Cameron Hogg4 Statistics and Data Management, SPD Development Company Limited, Bedford, UK.ORCID 0000-0002-7282-8160
Sarah Johnson1 Scientific and Medical Affairs, SPD Swiss Precision Diagnostics Development Company Limited, Bedford, UK.
William Ledger5 School of Women's and Children's Health, University of New South Wales, Sydney, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesA prospective, randomized controlled trial in women seeking to conceive examined the impact of using ovulation tests on self-reported levels of stress, psychological well-being, and quality of life in women with unexplained infertility.

methodThe test group used a home ovulation test to detect the day of ovulation, whereas the control group were provided with a predicted day of ovulation based on the average length of menstrual cycle reported during study recruitment. Volunteers collected their first morning urine samples to evaluate biochemical levels of stress (urinary cortisol and estrone-3-glucouronide) and completed questionnaires over two complete menstrual cycles.

resultsOverall, the use of digital ovulation tests by sub-fertile women under medical care had negligible negative effects and no detectable positive benefit on psychological well-being, according to multiple measurements of stress by questionnaire and biochemical markers. No significant differences were found between groups for all stress measures at the various study time points, except in relation to "couple concordance" where the test group scored much higher than the control group (mean difference at end of study was 21.25 (95% confidence interval: 9.25, 33.25; P = 0.0015)). The maximum difference in log cortisol: creatinine ratio between the test and control groups was -0.28 (95% confidence interval: -0.69, 0.13).

conclusionsThese results do not support propositions that using digital ovulation tests can cause stress in women trying to conceive.

Indexed as

AdultEstroneFemaleHumansHydrocortisoneInfertilityOvulationPoint-of-Care SystemsProspective StudiesStress, PsychologicalWomen's HealthEstroneestrone-3-glucuronideHydrocortisonecortisolinfertilityovulation testsquestionnairestresstimed intercourse

Identifiers

PMID30924413
PMCPMC6444416

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.