Evidence map›Paper›PMID 30924083›Full record

ArticleEndocrine2019

Body fat indices as effective predictors of insulin resistance in obese/non-obese polycystic ovary syndrome women in the Southwest of China.

Xin Huang, Qiuyi Wang, Tingting Liu, Tianjiao Pei, Dong Liu, Huili Zhu, Wei Huang

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Article in Endocrine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Biomarkers in Polycystic Ovary Syndrome.Current opinion in physiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xin HuangDepartment of Obstetrics and Gynecology, West China Second University Hospital of Sichuan University, Chengdu, 610041, Sichuan, China.
Qiuyi WangDepartment of Obstetrics and Gynecology, West China Second University Hospital of Sichuan University, Chengdu, 610041, Sichuan, China.
Tingting LiuDepartment of Obstetrics and Gynecology, West China Second University Hospital of Sichuan University, Chengdu, 610041, Sichuan, China.
Tianjiao PeiDepartment of Obstetrics and Gynecology, West China Second University Hospital of Sichuan University, Chengdu, 610041, Sichuan, China.
Dong LiuDepartment of Obstetrics and Gynecology, West China Second University Hospital of Sichuan University, Chengdu, 610041, Sichuan, China.
Huili ZhuDepartment of Obstetrics and Gynecology, West China Second University Hospital of Sichuan University, Chengdu, 610041, Sichuan, China.
Wei HuangDepartment of Obstetrics and Gynecology, West China Second University Hospital of Sichuan University, Chengdu, 610041, Sichuan, China. weihuang64@163.com.ORCID 0000-0001-9306-588X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeInsulin resistance (IR) is a common feature of polycystic ovary syndrome (PCOS). Body fat indices can be predictive markers of IR. This study is aimed to predict IR in Chinese women with PCOS of different body types based on body fat indices.

methodsA total of 723 women diagnosed with PCOS according to Rotterdam criteria were recruited in this study and were further divided into two groups based on their BMI. All participants underwent physical examinations and ultrasound; and blood was collected from them on the days 3-5 of the menstrual cycle. Their BMI, waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), lipid accumulation product (LAP) index, visceral adiposity index (VAI), and the homeostasis model assessment index of insulin resistance (HOMA-IR) were calculated. The correlations between body fat indices and HOMA-IR and receiver operating characteristic (ROC) curves were evaluated.

resultsIn normal weight group (BMI < 24, n = 333), VAI (best cut-off value: 1.681, area under curve (AUC) = 0.754, P < 0.01) and LAP index (best cut-off value: 18.53, AUC = 0.734, P < 0.001) were the reliable indicators of IR based on HOMA-IR ≥ 2.77, while in overweight/obese group (BMI ≥ 24, n = 390), the BMI, WC, WHtR and LAP index had a significant correlation with HOMA-IR. The representative markers to assess IR were BMI (best cut-off value: 26.43, AUC = 0.644, P = 0.001) and WHtR (best cut-off value: 0.544, AUC = 0.604, P = 0.021).

conclusionsBody fat indices are predictive markers of IR in Chinese PCOS women, especially in those with normal weight.

Indexed as

Insulin ResistanceAdipose TissueAdiposityAdultBody Mass IndexChinaCross-Sectional StudiesFemaleHealth Status IndicatorsHumansObesityPolycystic Ovary SyndromePrognosisYoung AdultBody fat indexesBody mass indexesInsulin resistancePolycystic ovary syndrome

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.