Evidence map›Paper›PMID 30923876›Full record

ReviewPediatric radiology2019

Gadolinium-based contrast agents - review of recent literature on magnetic resonance imaging signal intensity changes and tissue deposits, with emphasis on pediatric patients.

Einat Blumfield, David W Swenson, Ramesh S Iyer, A Luana Stanescu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Hybrid FeInternational journal of molecular sciences · 2026
    Article
  3. Receptor-Mediated SPION Labeling of CD4Nanomaterials (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Effect of EuRSC advances · 2025
    Article
  6. Review
  7. Gadolinium Contrast Agent Deposition in Children.Journal of magnetic resonance imaging : JMRI · 2025
    Review
  8. A deep learning model to enhance the classification of primary bone tumors based on incomplete multimodal images in X-ray, CT, and MRI.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Einat BlumfieldDepartment of Radiology, Children's Hospital of Montefiore, Albert Einstein College of Medicine, 111E 210th St, Bronx, NY, 10461, USA. Eblumfie@montefiore.org.ORCID http://orcid.org/0000-0002-9089-572X
David W SwensonDepartment of Diagnostic Imaging, Alpert Medical School of Brown University, Rhode Island Hospital/Hasbro Children's Hospital, Providence, RI, USA.
Ramesh S IyerDepartment of Radiology, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, WA, USA.
A Luana StanescuDepartment of Radiology, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, WA, USA.
Seattle Children's Hospital · USAlbert Einstein College of Medicine · USBrown University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gadolinium has been used as a base for contrast agents in MRI for the last three decades. Numerous studies over the last 4 years have reported increased signal intensity in deep brain nuclei in non-contrast MRI images following gadolinium-based contrast agent (GBCA) administration. Pathology studies performed on adults and children, and rodent necropsy studies have also shown gadolinium deposition in brain and other tissues after GBCA administration. The purpose of this review was to summarize and discuss the knowledge gained from these reports and the relevance for imaging pediatric patients.

Indexed as

Magnetic Resonance ImagingBrainChildContrast MediaGadoliniumHumansInjections, IntravenousContrast MediaGadoliniumBrainChildrenDepositionGadoliniumGadolinium-based contrast agentsMagnetic resonance imagingT1 signal

Identifiers

PMID30923876
OpenAlexW2934238100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.