RevieweNeuro
Echoes of Emotions Past: How Neuromodulators Determine What We Recollect.
Review in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed.
- Alpha-2 Adrenoreceptor Antagonist Yohimbine Potentiates Consolidation of Conditioned Fear.The international journal of neuropsychopharmacology · 2022Trial
- Identification of an intrusive-hypervigilant phenotype of posttraumatic stress symptoms with unique stress peptide and amygdala functional connectivity profiles.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Cognitive reappraisal influences the organization of emotional episodes in memory.Cognitive, affective & behavioral neuroscience · 2026Article
- Task-irrelevant stimuli robustly drive phasic pupil-linked arousal but only weakly affect memory formation.Scientific reports · 2026Article
- A dynamic affective surprise signal influences episodic memory.Cognition · 2026Article
- Arousal state modulates human hippocampal ripples.bioRxiv : the preprint server for biology · 2026Article
- The role of working memory in encoding the temporal structure of events in episodic memory: Evidence from a dual-task paradigm.Memory & cognition · 2026Article
- The temporal organization of memory and emotion is reciprocally coupled.bioRxiv : the preprint server for biology · 2026Article
- Dopaminergic processes predict temporal distortions in event memory.Nature communications · 2026Article
- Affective schemas: Acquisition, updating, and inference.Emotion (Washington, D.C.) · 2026Article
- AI-guided digital intervention with physiological monitoring reduces intrusive memories after experimental trauma.NPJ digital medicine · 2025Article
- Dynamic brain mechanisms supporting salient memories under cortisol.Science advances · 2025Article
- Neural Representation of Episodic Time.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Targeting memory of embedded positive verbal content indirectly modulates negative visual memory.iScience · 2025Article
- Noradrenergic activation of the basolateral amygdala facilitates memory specificity for similar events experienced close in time.Nature neuroscience · 2025Article
- Temporal memory for threatening events encoded in a haunted house.Cognition & emotion · 2025Article
- Goal orientation shifts attentional focus and impairs reward-motivated memory.Learning & memory (Cold Spring Harbor, N.Y.) · 2025Article
- Emotion Regulation Under Stress: A Social Processing and Memory Perspective.Current topics in behavioral neurosciences · 2025Review
- Positive affect amplifies integration within episodic memories in the laboratory and the real world.Learning & memory (Cold Spring Harbor, N.Y.) · 2025Article
- Integrating and fragmenting memories under stress and alcohol.Neurobiology of stress · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
We tend to re-live emotional experiences more richly in memory than more mundane experiences. According to one recent neurocognitive model of emotional memory, negative events may be encoded with a larger amount of sensory information than neutral and positive events. As a result, there may be more perceptual information available to reconstruct these events at retrieval, leading to memory reinstatement patterns that correspond with greater memory vividness and sense of recollection for negative events. In this commentary, we offer an alternative perspective on how emotion may influence such sensory cortex reinstatement that focuses on engagement of the noradrenergic (NE) and dopaminergic (DA) systems rather than valence. Specifically, we propose that arousal-related locus coeruleus-norepinephrine (LC-NE) system activation promotes the prioritization of the most salient features of an emotional experience in memory. Thus, a select few details may drive lower-level sensory cortical activity and a stronger sense of recollection for arousing events. By contrast, states of high behavioral activation, including novelty-seeking and exploration, may recruit the DA system to broaden the scope of cognitive processing and integrate multiple event aspects in memory. These more integrated memory representations may be reflected in higher-order cortical reinstatement at retrieval. Thus, the balance between activation in these neuromodulatory systems at encoding, rather than the valence of the event, may ultimately determine the quality of emotional memory recollection and neural reinstatement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.