Evidence map›Paper›PMID 30923672›Full record

ArticleInternational journal for parasitology. Parasites and wildlife2019

Age affects antibody levels and anthelmintic treatment efficacy in a wild rodent.

Melanie Clerc, Simon A Babayan, Andy Fenton, Amy B Pedersen

Open access · goldAbstract read
In one paragraph

Article in International journal for parasitology. Parasites and wildlife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Corticosterone Under Experimental Manipulation of Nutrition and Parasite Burden in a Wild Rodent System.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2026
    Article
  2. Article
  3. Article
  4. Divergent age-related changes in parasite infection occur independently of behaviour and demography in a wild ungulate.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Article
  5. Article
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  7. Ontogeny of immunity and potential implications for co-infection.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Melanie ClercInstitute of Evolutionary Biology and Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3FL, UK.
Simon A BabayanInstitute of Biodiversity, Animal Health & Comparative Medicine, University of Glasgow, Glasgow, G12 8QQ, UK.
Andy FentonInstitute of Integrative Biology, University of Liverpool, Liverpool, L69 7ZB, UK.
Amy B PedersenInstitute of Evolutionary Biology and Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3FL, UK.
Centre for Immunity, Infection and Evolution · GBUniversity of Edinburgh · GBUniversity of Glasgow · GBUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of the host immune system in determining parasite burdens and mediating within-host parasite interactions has traditionally been studied in highly controlled laboratory conditions. This does, however, not reflect the diversity of individuals living in nature, which is often characterised by significant variation in host demography, such as host age, sex, and infection history. Whilst studies using wild hosts and parasites are beginning to give insights into the complex relationships between immunity, parasites and host demography, the cause-and-effect relationships often remain unknown due to a lack of high resolution, longitudinal data. We investigated the infection dynamics of two interacting gastrointestinal parasites of wild wood mice (

Indexed as

Age-dependent immunityAnthelmintic treatmentEimeria hungaryensisHeligmosomoides polygyrusWild immunologyWithin-host interaction

Identifiers

PMID30923672
PMCPMC6423487
OpenAlexW2922420112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.