Evidence map›Paper›PMID 30923634›Full record

ReviewJournal of nucleic acids2019

Netrin Family: Role for Protein Isoforms in Cancer.

Caroline Suzanne Bruikman, Huayu Zhang, Anneli Maite Kemper, Janine Maria van Gils

Open access · goldAbstract readReview
In one paragraph

Review in Journal of nucleic acids, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Expression of Netrin-1 in the developing mouse heart.Gene expression patterns : GEP · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Hepatic Expression of NTN4 and Its Receptors in Patients with Hepatocellular Carcinoma.Asian Pacific journal of cancer prevention : APJCP · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Netrin-1: A Modulator of Macrophage Driven Acute and Chronic Inflammation.International journal of molecular sciences · 2021
    Review
  20. Netrin-1 in Glioblastoma Neovascularization: The New Partner in Crime?International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Caroline Suzanne BruikmanAmsterdam UMC, University of Amsterdam, Department of Vascular Medicine, Location Meibergdreef, Amsterdam, Netherlands.
Huayu ZhangLeiden University Medical Center, Department of Internal Medicine, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden, Netherlands.
Anneli Maite KemperLeiden University Medical Center, Department of Internal Medicine, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden, Netherlands.
Janine Maria van GilsLeiden University Medical Center, Department of Internal Medicine, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden, Netherlands.ORCID 0000-0003-2429-7462
Leiden University Medical Center · NLAmsterdam University Medical Centers · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Netrins form a family of secreted and membrane-associated proteins. Netrins are involved in processes for axonal guidance, morphogenesis, and angiogenesis by regulating cell migration and survival. These processes are of special interest in tumor biology. From the netrin genes various isoforms are translated and regulated by alternative splicing. We review here the diversity of isoforms of the netrin family members and their known and potential roles in cancer.

Identifiers

PMID30923634
PMCPMC6408995
OpenAlexW2916889903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.