Evidence map›Paper›PMID 30923581›Full record

ArticlePolymer chemistry2018

Peptide-Dendron Hybrids that Adopt Sequence-Encoded β-Sheet Conformations.

Deborah A Barkley, Sang Uk Han, Tadanori Koga, Jonathan G Rudick

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymer chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Deborah A BarkleyDepartment of Chemistry, Stony Brook University, Stony Brook, New York 11794, United States.
Sang Uk HanDepartment of Chemistry, Stony Brook University, Stony Brook, New York 11794, United States.
Tadanori KogaDepartment of Chemistry, Stony Brook University, Stony Brook, New York 11794, United States.
Jonathan G RudickDepartment of Chemistry, Stony Brook University, Stony Brook, New York 11794, United States.

Funding

Acquisition of an Applied Biosystems 4000 QTRAP Mass SpectrometerS10RR023680 · NCRR · STATE UNIVERSITY NEW YORK STONY BROOK · PI IDEN, CHARLES R · 2007 to 2007
$435k
NCRR NIH HHS S10 RR023680
6 · The paper itself

Abstract

Rational design rules for programming hierarchical organization and function through mutations of monomers in sequence-defined polymers can accelerate the development of novel polymeric and supramolecular materials. Our strategy for designing peptide-dendron hybrids that adopt predictable secondary and quaternary structures in bulk is based on patterning the sites at which dendrons are conjugated to short peptides. To validate this approach, we have designed and characterized a series of β-sheet-forming peptide-dendron hybrids. Spectroscopic studies of the hybrids in films reveal that the peptide portion of the hybrids adopts the intended secondary structure.

Identifiers

PMID30923581
PMCPMC6433408

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.