Evidence map›Paper›PMID 30923573›Full record

ArticleTherapeutic advances in gastroenterology2019

Proton-pump inhibitors do not influence clinical outcomes in patients with

Aisling R Caffrey, Tristan T Timbrook, Syed Raza Ali, Victor Nizet, George Sakoulas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Therapeutic advances in gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Aisling R CaffreyVeterans Affairs Medical Center, Infectious Diseases Research Program and Center of Innovation in Long-Term Services and Supports, Providence, Rhode Island, USA.ORCID https://orcid.org/0000-0002-4180-027X
Tristan T TimbrookVeterans Affairs Medical Center, Infectious Diseases Research Program and Center of Innovation in Long-Term Services and Supports, Providence, Rhode Island, USA.
Syed Raza AliSchool of Medicine, University of California, San Diego, CA, USA.
Victor NizetSchool of Medicine, University of California, San Diego, CA, USA.
George SakoulasSchool of Medicine, University of California, San Diego, CA, USA.
University of California San Diego · USProvidence College · USUniversity of Rhode Island · US

Funding

Safety and Dose Optimization of High-Dose Anakinra in Kawasaki DiseaseU54HD090259 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CAPPARELLI, EDMUND VINCENT, NIZET, VICTOR · 2016 to 2018
$2.2M
NICHD NIH HHS U54 HD090259
6 · The paper itself

Abstract

backgroundProton-pump inhibitors (PPIs) are commonly used in clinical practice for gastric acid suppression. However, these agents have also been associated with certain negative clinical outcomes. We evaluated the real-world effects of incident PPI use on clinical outcomes in patients with

methodsThis retrospective cohort study included patients admitted to Veterans Affairs hospitals with positive

resultsClinical outcomes, including inpatient mortality, intensive care discharge, 30-day mortality, 30-day readmission, and 30-day

conclusionsIn our large national cohort study, PPIs were not associated with an increased risk of negative clinical outcomes, including mortality and CDI, in patients with

Indexed as

bacteremiaClostridium difficilemortalityproton-pump inhibitorsStaphylococcus aureus

Identifiers

PMID30923573
PMCPMC6431768
OpenAlexW2924448382

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.