Evidence map›Paper›PMID 30923567›Full record

ArticleBiotechnology for biofuels2019

QTL analysis reveals genomic variants linked to high-temperature fermentation performance in the industrial yeast.

Zhen Wang, Qi Qi, Yuping Lin, Yufeng Guo, Yanfang Liu, Qinhong Wang

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
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  7. Genotypic and Phenotypic Diversity ofJournal of fungi (Basel, Switzerland) · 2023
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  15. Random Transfer ofJournal of fungi (Basel, Switzerland) · 2021
    Article
  16. Article
  17. Rapid Enabling ofFrontiers in bioengineering and biotechnology · 2021
    Article
  18. Article
  19. Selection and subsequent physiological characterization of industrialBiotechnology reports (Amsterdam, Netherlands) · 2020
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zhen Wang *1CAS Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308 China.
Qi Qi *1CAS Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308 China.
Yuping Lin1CAS Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308 China.
Yufeng Guo1CAS Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308 China.
Yanfang Liu1CAS Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308 China.
Qinhong Wang1CAS Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308 China.
Chinese Academy of Sciences · CNTianjin Institute of Industrial Biotechnology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh-temperature fermentation is desirable for the industrial production of ethanol, which requires thermotolerant yeast strains. However, yeast thermotolerance is a complicated quantitative trait. The understanding of genetic basis behind high-temperature fermentation performance is still limited. Quantitative trait locus (QTL) mapping by pooled-segregant whole genome sequencing has been proved to be a powerful and reliable approach to identify the loci, genes and single nucleotide polymorphism (SNP) variants linked to quantitative traits of yeast.

resultsOne superior thermotolerant industrial strain and one inferior thermosensitive natural strain with distinct high-temperature fermentation performances were screened from 124

conclusionsThis work revealed eight novel causative genes and SNP variants closely associated with high-temperature fermentation performance. Among these genes,

Indexed as

Allele replacementHigh-temperature fermentation (HTF)Pooled-segregant whole-genome sequence analysisQTL mappingReciprocal hemizygosity analysisSaccharomyces cerevisiae

Identifiers

PMID30923567
PMCPMC6423876
OpenAlexW2937889184

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.