Evidence map›Paper›PMID 30923438›Full record

ArticleInfectious diseases in clinical practice (Baltimore, Md.)2018

Zika Virus-Associated Guillain-Barré Syndrome in a Returning US Traveler.

Jason Beattie, Sunita Parajuli, Matthew Sanger, Gregory Lee, Perrin Pleninger, George Crowley, Sophia Kwon, Vivek Murthy, Jeffrey A Manko, Arthur Caplan and 3 more

Open access · greenAbstract read
In one paragraph

Article in Infectious diseases in clinical practice (Baltimore, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  13. Virus Detection: From State-of-the-Art Laboratories to Smartphone-Based Point-of-Care Testing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Jason BeattieDepartment of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, New York University, School of Medicine.
Sunita ParajuliDepartment of Medicine, Division of Infectious Diseases, New York University, School of Medicine.
Matthew SangerDepartment of Neurology, New York University, School of Medicine.
Gregory LeeDepartment of Medicine, Division of Infectious Diseases, New York University, School of Medicine.
Perrin PleningerDepartment of Neurology, New York University, School of Medicine.
George CrowleyDepartment of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, New York University, School of Medicine.
Sophia KwonDepartment of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, New York University, School of Medicine.
Vivek MurthyDepartment of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, New York University, School of Medicine.
Jeffrey A MankoDepartment of Emergency Medicine, New York University, School of Medicine.
Arthur CaplanDivision of Ethics, Department of Population Health, New York University, School of Medicine.
Elizabeth DufortNew York State Department of Health, Division of Epidemiology, Albany, NY.
Daniel M PastulaDepartments of Neurology, Medicine, and Epidemiology, University of Colorado Denver, Aurora, CO.
Anna NolanDepartment of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, New York University, School of Medicine.
Neurology, Inc · USNew York University · USOffice of Infectious Diseases · USPulmonary and Critical Care Associates · USSleepMed · USNew York State Department of Health · USUniversity of Colorado Denver · US

Funding

Metabolomics of World Trade Center-Lung Injury: Biomarker Validation, Longitudinal Assessment and Dietary InterventionU01OH011300 · OH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI NOLAN, ANNA · 2017 to 2025
$4.8M
RAGE Mediates LPA Induced Pulmonary InflammationR01HL119326 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI NOLAN, ANNA · 2015 to 2019
$2.1M
NHLBI NIH HHS R01 HL119326NIOSH CDC HHS U01 OH011300
6 · The paper itself

Abstract

Zika virus (ZIKV) infection has been associated with Guillain-Barré Syndrome (GBS). Roughly 60% of people in countries such as the U.S. live in areas at risk for seasonal spread of ZIKV. ZIKV belongs to a class of diseases that is not typically seen in hospital settings across the U.S. and Europe. We describe the case presentation, management, and treatment of ZIKV infection complicated by GBS. A 64-year-old woman with recent travel to the Dominican Republic presented with rash followed by an acute, ascending polyneuropathy consistent with GBS. She was confirmed to have an acute ZIKV infection by detection of ZIKV nucleic acid by reverse transcription-polymerase chain reaction. She met Brighton Collaboration criteria level 1 evidence for GBS. She received two courses of intravenous immunoglobulin and slowly improved, though still had weakness at discharge. More research is needed to identify the pathophysiology behind ZIKV-associated GBS and its optimal treatment. Prevention is fundamental to limiting infection and spread of ZIKV.

Identifiers

PMID30923438
PMCPMC6433380
OpenAlexW2802477764

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.