Evidence map›Paper›PMID 30923355›Full record

ArticleScientific reports2019

RNA interference-mediated knockdown of voltage-gated sodium channel (MpNa

Kaleem Tariq, Asad Ali, T G Emyr Davies, Erum Naz, Laila Naz, Summar Sohail, Maolin Hou, Farman Ullah

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
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  5. Two detoxification enzyme genes,Frontiers in physiology · 2024
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  9. Silencing ofInsects · 2022
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  12. Transposon-mediated insertional mutagenesis unmasks recessive insecticide resistance in the aphidProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. TheFrontiers in physiology · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Kaleem TariqDepartment of Agriculture, Abdul Wail Khan University, Mardan, Khyber Pakhtunkhwa, Pakistan. drkaleem@awkum.edu.pk.
Asad AliDepartment of Agriculture, Abdul Wail Khan University, Mardan, Khyber Pakhtunkhwa, Pakistan.
T G Emyr DaviesDepartment of Biointeractions and Crop Protection, Rothamsted Research, Harpenden, Hertfordshire, AL5 2JQ, UK.
Erum NazDepartment of Agriculture, Abdul Wail Khan University, Mardan, Khyber Pakhtunkhwa, Pakistan.
Laila NazDepartment of Agriculture, Abdul Wail Khan University, Mardan, Khyber Pakhtunkhwa, Pakistan.
Summar SohailState Key Laboratory of Agricultural Microbiology; Hubei Key Laboratory of Insect Resource Application and Sustainable Pest Control, Huazhong Agricultural University, Wuhan, 430070, Hubei, China.
Maolin HouState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Farman UllahDepartment of Entomology, College of Plant protection, China Agriculture University, Beijing, 100193, China.
Abdul Wali Khan University Mardan · PKChina Agricultural University · CNChinese Academy of Agricultural Sciences · CNInstitute of Plant Protection · CNRothamsted Research · GBState Key Laboratory of Agricultural Microbiology

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Voltage-gated sodium channels (VGSC) are transmembrane proteins that generate an action potential in excitable cells and play an essential role in neuronal signaling. Since VGSCs play a crucial role in nerve transmission they have become primary targets for a broad range of commercial insecticides. RNA interference (RNAi) is a valuable reverse genetics tool used in functional genomics, but recently, it has also shown promise as a novel agent that could be used to control agricultural insect pests. In this study, we targeted the VGSC (MpNa

Indexed as

Biological Control AgentsRNA InterferenceAnimalsAphidsCrop ProductionFertilityGene Knockdown TechniquesGenes, InsectLongevityPrunus persicaReverse GeneticsRNA, Double-StrandedSolanum tuberosumTime FactorsVoltage-Gated Sodium ChannelsBiological Control AgentsRNA, Double-StrandedVoltage-Gated Sodium Channels

Identifiers

PMID30923355
PMCPMC6439219
OpenAlexW2924528028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.