ArticleScientific reports2019
Breast cancer occurrence after low dose radiotherapy of non-malignant disorders of the shoulder.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Can Low-Dose Radiation Therapy Aid in Chronic Subdural Hematoma Management? A Historical Review.Advances in radiation oncology · 2026Review
- Implementing a low-dose radiation therapy program for musculoskeletal pain disorders: tips, tricks, and essentials for clinical researchers.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Review
- Low-dose radiotherapy for painful osteoarthritis of the elderly: A multicenter analysis of 970 patients with 1185 treated sites.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021Article
- Low-dose radiation therapy (LDRT) for COVID-19 and its deadlier variants.Archives of toxicology · 2021Article
- First Insights into the Effect of Low-Dose X-Ray Irradiation in Adipose-Derived Stem Cells.International journal of molecular sciences · 2019Article
- Immunomodulation Through Low-Dose Radiation for Severe COVID-19: Lessons From the Past and New Developments.Dose-response : a publication of International Hormesis SocietyReview
- Lack of Relevant Haemogram Changes During Percutaneous Radiotherapy of Localised Prostate Cancer.In vivo (Athens, Greece)Article
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Stochastic long-term damages at relatively low doses have the potential for cancer induction. For the first time we investigated the occurrence of breast cancer in female patients after radiotherapy of non-malignant disorders of the shoulder and made a comparison with the estimated spontaneous incidence of mammary carcinoma for this cohort. In a geographically defined district with a population of approximately 100.000 inhabitants, comprehensive data of radiological diagnostics and radiotherapy were registered nearly completely for 41 years; data included mammography and radiotherapy of breast cancer patients as well as of non-malignant disorders. Within this population a collective of 158 women with radiotherapy of the shoulder was investigated. Radiotherapy was performed with cobalt-60 photons (Gammatron) with an average cumulative-dose of 6 Gy. The average follow-up time was 21.3 years. Patients were 55 years old (median) when radiotherapy of the shoulder was performed. Seven patients (4.4%) developed breast cancer after a median of 21 years. According to the incidence statistics, 9.4 +/- 1.8 (95%CI) cases (5.9%) would be expected. In regard to the irradiated shoulder neither the ipsilateral nor the contralateral breasts showed increased rates of breast cancer. An induction of additional breast cancer caused by radiation of non-malignant disorders of the shoulder wasn't detected in the investigated cohort.
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