ArticleScience (New York, N.Y.)2019
The entorhinal cognitive map is attracted to goals.
Article in Science (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.
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Who cites it
102 citing papers in PubMed.
- Structured experience shapes strategy learning and neural dynamics in the medial entorhinal cortex.Nature neuroscience · 2026Article
- Subicular spatial codes arise from predictive mapping.Nature communications · 2026Article
- Subicular plateaus signal reward locations during goal-directed behavior.Cell reports · 2026Article
- Coordinating Cognition: The Entorhinal Cortex in Mnemonic, Temporal and Spatial Representation.Cells · 2026Review
- Grid maps are disrupted after large-scale arena expansion and recover with experience.Nature communications · 2026Article
- Flexible goal learning involves coordinated population activity in dCA1 and medial orbitofrontal cortex.PLoS biology · 2026Article
- Action information is integrated into entorhinal representations of conceptual space and is reflected in eye movements.PLoS biology · 2026Article
- Egocentric Dominance in Spatial Representations: The Role of Environmental Familiarity in Building Cognitive Maps.Brain and behavior · 2026Article
- Directional dynamics in the entorhinal cortex of male mice driven by behavioral constraints.Nature communications · 2026Article
- Gaussian Process Inference Reveals Non-separability of Position and Velocity Tuning in Grid Cells.bioRxiv : the preprint server for biology · 2026Article
- Subicular Plateaus Signal Reward Locations during Goal-Directed Behavior.bioRxiv : the preprint server for biology · 2026Article
- Aberrant medial entorhinal cortex dynamics link tau pathology to spatial memory impairment.bioRxiv : the preprint server for biology · 2026Article
- The perforant pathway and CA3-Schaffer collateral afferents coordinate to regulate spatial learning.Communications biology · 2026Article
- Activation of the medial entorhinal cortex drives memory-guided navigation behavior.bioRxiv : the preprint server for biology · 2025Article
- Slow synaptic plasticity from the hippocampus underlies gradual mapping and fragmentation of novel spaces by grid cells.bioRxiv : the preprint server for biology · 2025Article
- Grid cells accurately track movement during path integration-based navigation despite switching reference frames.Nature neuroscience · 2025Article
- Distinct brain regions map olfactory and visual spaces.bioRxiv : the preprint server for biology · 2025Article
- Speed modulations in grid cell information geometry.Nature communications · 2025Article
- Reconciling flexibility and efficiency: medial entorhinal cortex represents a compositional cognitive map.Nature communications · 2025Article
- A flexible hippocampal population code for experience relative to reward.Nature neuroscience · 2025Article
42 more citing papers are in PubMed but not listed here.
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5 authors.
Funding
Abstract
Grid cells with their rigid hexagonal firing fields are thought to provide an invariant metric to the hippocampal cognitive map, yet environmental geometrical features have recently been shown to distort the grid structure. Given that the hippocampal role goes beyond space, we tested the influence of nonspatial information on the grid organization. We trained rats to daily learn three new reward locations on a cheeseboard maze while recording from the medial entorhinal cortex and the hippocampal CA1 region. Many grid fields moved toward goal location, leading to long-lasting deformations of the entorhinal map. Therefore, distortions in the grid structure contribute to goal representation during both learning and recall, which demonstrates that grid cells participate in mnemonic coding and do not merely provide a simple metric of space.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.