ArticleScience (New York, N.Y.)2019
Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection.
Open access · greenAbstract read
In one paragraph
Article in Science (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 284 papers.
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0cells of the map it votes in
284citing papers in PubMed
39.8field-weighted citation impact, top 1% of its field
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Who cites it
284 citing papers in PubMed, 459 citations in OpenAlex.
- Adjunctive Probiotics Alleviates Asthmatic Symptoms via Modulating the Gut Microbiome and Serum Metabolome.Microbiology spectrum · 2021Trial
- Smaller Genomes and Shorter Prophage Sequences Differentiate Clinical from Environmental Isolates ofbioRxiv : the preprint server for biology · 2026Article
- Unlocking the potential of bacteriophage-based therapeutic gene delivery in hepatocellular carcinoma.Journal of the Egyptian National Cancer Institute · 2026Review
- A novel cystic fibrosis-mimetic Pseudomonas auxotrophic vaccine is protective in vivo and is associated with IL-17/IgA mucosal Immunity.Molecular therapy : the journal of the American Society of Gene Therapy · 2026Article
- Targeting the human gut microbiome: a comparative review of probiotics, prebiotics, synbiotics, and postbiotics.Journal of advanced research · 2026Review
- Antibodies targeting phage fiber and nozzle proteins impair Acinetobacter baumannii phage therapy by blocking infection and promoting immune clearance.PLoS biology · 2026Article
- Phage therapy: from basic biology to clinical application.Nature reviews. Microbiology · 2026Review
- Single-step monolithic chromatography efficiently purifies diverse Pseudomonas aeruginosa phages with therapeutic-grade endotoxin reduction.Npj viruses · 2026Article
- Protecting Newborns from Multidrug-Resistant Infections: The Emerging Role of Bacteriophages.Viruses · 2026Review
- Prophages in Skin Pathogens: From Virulence to Therapy.Pathogens (Basel, Switzerland) · 2026Review
- Disrupting phage liquid crystalline droplets restores antibiotic susceptibility in Pseudomonas aeruginosa biofilms.PLoS biology · 2026Article
- Lung Microbiome Diversity, Infection Dynamics, and Microbe-Mediated Cross-Protection.MicrobiologyOpen · 2026Review
- Trans-Kingdom dsRNA Sensing:bioRxiv : the preprint server for biology · 2026Article
- Immune Responses to Phage Therapy in Humans: A Review.The Journal of infectious diseases · 2026Review
- Alternating High-Fat and Polysaccharide Diets Modulates Gut Phage-Bacterial Interplay.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Phage Therapy: Targeting the Gut Microbiota for the Treatment of Acute Pancreatitis.Journal of gastroenterology and hepatology · 2026Review
- Therapeutic and immunomodulatory effects of phage therapy in red hybrid tilapia challenged with Klebsiella pneumoniae.Archives of microbiology · 2026Article
- Phosphorylation of PfiA modulates Pf4 phage production through PfiA/PfiT stoichiometric reconfiguration inScience advances · 2026Article
- Engineered Bacteriophages: A Next-Generation Platform for Precision Antimicrobials and Therapeutics.Viruses · 2026Review
- Dysbiosis of the enteric DNA virome correlates with the development of cachexia in a murine Lewis lung carcinoma (LLC) model.Archives of virology · 2026Article
224 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
21 authors at 5 institutions in 1 country.
Johanna M SweereDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0002-9602-8117
Jonas D Van BelleghemDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0003-0002-024X
Heather IshakDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0001-8592-340X
Michelle S BachDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0002-3425-5234
Medeea PopescuDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0001-6856-5559
Vivekananda SunkariDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.
Gernot KaberDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.
Robert ManasherobDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.
Gina A SuhDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0001-7434-6897
Xiou CaoDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0001-7202-6582
Christiaan R de VriesDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0002-4667-5973
Dung N LamDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.
Payton L MarshallDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0002-0921-3016
Maria BirukovaDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.
Ethan KatznelsonDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.
Daniel V LazzareschiDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.
Swathi BalajiDivision of Pediatric Surgery, Department of Surgery, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0001-8875-8008
Sundeep G KeswaniDivision of Pediatric Surgery, Department of Surgery, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-8820-0706
Thomas R HawnDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA, USA.ORCID 0000-0003-2368-3185
Patrick R SecorDivision of Biological Sciences, University of Montana, Missoula, MT, USA.ORCID 0000-0001-7123-3037
Paul L BollykyDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA. pbollyky@stanford.edu.ORCID 0000-0003-2499-9448
Stanford University · USBaylor College of Medicine · USPalo Alto Veterans Institute for Research · USUniversity of Montana · USUniversity of Washington · US
Funding
MOLECULAR &CELLULAR IMMUNOBIOLOGYT32AI007290 · NIAID · STANFORD UNIVERSITY · PI Sean Curtis Bendall, Olivia M Martinez · 1985 to 2026
$27.0MStanford Islet Research CoreP30DK116074 · NIDDK · STANFORD UNIVERSITY · PI Seung K Kim · 2017 to 2026
$19.5MSurveillance genome sequencing to detect SARS-CoV-2 virus variants in MontanaP20GM103546 · NIGMS · UNIVERSITY OF MONTANA · PI BOWLER, BRUCE E · 2012 to 2021
$19.2MImmunization against filamentous bacteriophages to prevent bacterial infectionR01AI138981 · NIAID · UNIVERSITY OF MONTANA · PI EVANS, JAY T. · 2018 to 2022
$5.4MNovel Mechanisms of Regenerative Wound HealingR01GM111808 · NIGMS · CINCINNATI CHILDRENS HOSP MED CTR · PI Sundeep G Keswani · 2014 to 2026
$3.6MLymph Node Extracellular Matrix in Antigen Presentation and Immune RegulationR01DK096087 · NIDDK · STANFORD UNIVERSITY · PI BOLLYKY, PAUL L · 2012 to 2021
$3.4MHeparanase and Regulatory T cell Stability and FunctionR21AI133240 · NIAID · STANFORD UNIVERSITY · PI BOLLYKY, PAUL L · 2018 to 2019
$438kPf Bacteriophages in the Pathophysiology of Cystic Fibrosis and Pseudomonas aeruginosa InfectionR21AI137432 · NIAID · STANFORD UNIVERSITY · PI BOLLYKY, PAUL L · 2018 to 2019
$437kTransmission Electron MicroscopeS10RR026780 · NCRR · STANFORD UNIVERSITY · PI TALBOT, WILLIAM S · 2010 to 2010
$412kBiofilms and Bacteriophages in Chronic Wound InfectionsR21AI133370 · NIAID · STANFORD UNIVERSITY · PI BOLLYKY, PAUL L · 2017 to 2017
$319kUnderstanding polymer-induced bacterial aggregation and antimicrobial toleranceK22AI125282 · NIAID · UNIVERSITY OF MONTANA · PI SECOR, PATRICK R · 2018 to 2019
$265kNCRR NIH HHS S10 RR026780NIAID NIH HHS K22 AI125282NIAID NIH HHS R01 AI138981NIAID NIH HHS R21 AI133240NIAID NIH HHS R21 AI133370NIAID NIH HHS R21 AI137432NIDDK NIH HHS P30 DK116074NIDDK NIH HHS R01 DK096087NIGMS NIH HHS P20 GM103546NIGMS NIH HHS R01 GM111808
Abstract
Bacteriophage are abundant at sites of bacterial infection, but their effects on mammalian hosts are unclear. We have identified pathogenic roles for filamentous Pf bacteriophage produced by
Indexed as
Immune ToleranceAdaptor Proteins, Vesicular TransportAnimalsAntibodies, ViralHumansInterferonsMaleMiceMice, Inbred C57BLMice, Mutant StrainsPhagocytosisPseudomonas aeruginosaPseudomonas InfectionsPseudomonas PhagesToll-Like Receptor 3Tumor Necrosis Factor-alphaAdaptor Proteins, Vesicular TransportAntibodies, ViralInterferonsTicam1 protein, mouseTLR3 protein, mouseToll-Like Receptor 3Tumor Necrosis Factor-alpha
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.