Evidence map›Paper›PMID 30923085›Full record

ArticleAJNR. American journal of neuroradiology2019

Morphologic Features on MR Imaging Classify Multifocal Glioblastomas in Different Prognostic Groups.

J Pérez-Beteta, D Molina-García, M Villena, M J Rodríguez, C Velásquez, J Martino, B Meléndez-Asensio, Á Rodríguez de Lope, R Morcillo, J M Sepúlveda and 8 more

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  4. Artificial intelligence-based MRI radiomics and radiogenomics in glioma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

J Pérez-BetetaFrom the Department of Mathematics (J.P.-B., D.M.-G., V.M.P.-G.), Mathematical Oncology Laboratory, Universidad de Castilla-La Mancha, Ciudad Real, Spain.ORCID 0000-0003-0317-6215
D Molina-GarcíaFrom the Department of Mathematics (J.P.-B., D.M.-G., V.M.P.-G.), Mathematical Oncology Laboratory, Universidad de Castilla-La Mancha, Ciudad Real, Spain david.molina@uclm.es.ORCID 0000-0002-6104-3894
M VillenaDepartments of Neurosurgery (M.V.).ORCID 0000-0001-7610-2992
M J RodríguezRadiology (M.J.R.), Hospital General de Ciudad Real, Ciudad Real, Spain.ORCID 0000-0002-4561-2858
C VelásquezDepartment of Neurosurgery (J.M., C.V.), Hospital Universitario Marqués de Valdecilla and Fundación, Instituto de Investigación Marqués de Valdecilla, Santander, Spain.ORCID 0000-0002-4443-5888
J MartinoDepartment of Neurosurgery (J.M., C.V.), Hospital Universitario Marqués de Valdecilla and Fundación, Instituto de Investigación Marqués de Valdecilla, Santander, Spain.ORCID 0000-0001-9605-3331
B Meléndez-AsensioDepartments of Molecular Biology (B.M.-A.).ORCID 0000-0001-5004-8895
Á Rodríguez de LopeNeurosurgery (Á.R.d.L.).ORCID 0000-0001-8959-5407
R MorcilloRadiology (R.M.), Hospital Virgen de la Salud, Toledo, Spain.ORCID 0000-0003-4977-9302
J M SepúlvedaDepartments of Neuro-Oncology (J.M.S.).ORCID 0000-0003-3548-9961
A Hernández-LaínPathology (A.H.-L.).ORCID 0000-0003-1642-4505
A RamosRadiology (A. Ramos), Hospital Universitario 12 de Octubre, Madrid, Spain.ORCID 0000-0002-8618-313X
J A BarciaDepartment of Neurosurgery (J.A.B.), Hospital Clínico San Carlos, Madrid, Spain.ORCID 0000-0001-6562-4568
P C LaraDepartment of Radiation Oncology (P.C.L.), San Roque University Hospital/Universidad Fernando Pessoa Canarias, Gran Canaria, Spain.ORCID 0000-0003-1709-6232
D AlbilloDepartment of Radiology (D.A.), Hospital Universitario de Salamanca, Salamanca, Spain.ORCID 0000-0002-4496-6849
A RevertDepartment of Radiology (A. Revert), Hospital de Manises, Valencia, Spain.ORCID 0000-0003-0515-7552
E AranaDepartment of Radiology (E.A.), Fundación Instituto Valenciano de Oncología, Valencia, Spain.ORCID 0000-0002-1884-7854
V M Pérez-GarcíaFrom the Department of Mathematics (J.P.-B., D.M.-G., V.M.P.-G.), Mathematical Oncology Laboratory, Universidad de Castilla-La Mancha, Ciudad Real, Spain.ORCID 0000-0002-6575-495X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeMultifocal glioblastomas (ie, glioblastomas with multiple foci, unconnected in postcontrast pretreatment T1-weighted images) represent a challenge in clinical practice due to their poor prognosis. We wished to obtain imaging biomarkers with prognostic value that have not been found previously. MATERIALS AND

methodsA retrospective review of 1155 patients with glioblastomas from 10 local institutions during 2006-2017 provided 97 patients satisfying the inclusion criteria of the study and classified as having multifocal glioblastomas. Tumors were segmented and morphologic features were computed using different methodologies: 1) measured on the largest focus, 2) aggregating the different foci as a whole, and 3) recording the extreme value obtained for each focus. Kaplan-Meier, Cox proportional hazards, correlations, and Harrell concordance indices (c-indices) were used for the statistical analysis.

resultsAge (

conclusionsA prognostic model incorporating imaging findings on pretreatment postcontrast T1-weighted MRI classified patients with glioblastoma into different prognostic groups.

Indexed as

AdultAgedBrain NeoplasmsFemaleGlioblastomaHumansMagnetic Resonance ImagingMaleMiddle AgedPrognosisProportional Hazards ModelsRetrospective StudiesSurvival Analysis

Identifiers

PMID30923085
PMCPMC7048517

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.