ArticleArchives of physical medicine and rehabilitation2019
The Effect of Frailty on Discharge Location for Medicare Beneficiaries After Acute Stroke.
Article in Archives of physical medicine and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Role of frailty in predicting outcomes after stroke: a systematic review and meta-analysis.Frontiers in psychiatry · 2024Pooled it
- Prevalence and Risk Factors of Frailty in Stroke Patients: A Meta-Analysis and Systematic Review.The journal of nutrition, health & aging · 2023Pooled it
- Prevalence and implications of frailty in acute stroke: systematic review & meta-analysis.Age and ageing · 2022Pooled it
- Frailty Syndromes in Persons With Cerebrovascular Disease: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2019Pooled it
- Is pre-stroke frailty as determined by the Clinical Frailty Scale version 2.0 associated with stroke outcomes?Singapore medical journal · 2026Article
- Narrative Review on Post-Stroke Outcomes Through Recognition of Frailty, Sarcopenia, and Palliative Care Needs.Healthcare (Basel, Switzerland) · 2025Review
- Frailty and stroke: Global implications for assessment, research, and clinical care-A WSO scientific statement.International journal of stroke : official journal of the International Stroke Society · 2025Review
- Frailty in Stroke Care in Germany Between 2016 and 2022-A Retrospective, Hospital-Based Nationwide Cohort Study.NeuroSci · 2025Article
- Association between Braden Scale and all-cause mortality in critically ill patients with non-traumatic subarachnoid hemorrhage: analysis of the MIMIC-IV database.Neurosurgical review · 2025Article
- Association between Pre-stroke Frailty and Clinical Outcomes: A Systematic Review and Meta-analysis.Physical therapy research · 2025Review
- The added value of frailty assessment as the premorbid stroke status on activities of daily living in patients with acute stroke, stratified by stroke severity.The journal of nutrition, health & aging · 2024Article
- Predictors of Discharge Destination After Stroke.Neurorehabilitation and neural repair · 2023Observational
- Effects of frailty on postoperative clinical outcomes of aneurysmal subarachnoid hemorrhage: results from the National Inpatient Sample database.BMC geriatrics · 2022Article
- Frailty and cerebrovascular disease: Concepts and clinical implications for stroke medicine.International journal of stroke : official journal of the International Stroke Society · 2022Review
- Association of Pre-stroke Frailty With Prognosis of Elderly Patients With Acute Cerebral Infarction: A Cohort Study.Frontiers in neurology · 2022Article
- Association between in-hospital frailty and health-related quality of life after stroke: the Nor-COAST study.BMC neurology · 2021Observational
- Pre-stroke disability and stroke severity as predictors of discharge destination from an acute stroke ward.Clinical medicine (London, England) · 2021Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo examine the effect of frailty on poststroke discharge location with respect to stroke severity and create a risk-adjusted model for understanding the effects of frailty on discharge to an inpatient rehabilitation facility.
designRetrospective cohort.
settingA 2014 5% Medicare sample.
participantsPatients hospitalized for a first-time acute ischemic stroke (N=7258).
interventionsNot applicable.
main outcome measuresA prehospitalization 6-month baseline was used to calculate a frailty score. Logistic regression to predict odds of discharge to inpatient rehabilitation was used to calculate for 3 levels of baseline frailty, controlling for patient demographics, stroke severity, and comorbidities.
resultsAbout 1603 patients were discharged to inpatient rehabilitation. Patients who were nonfrail (odds ratio [OR] 1.716; 95% confidence interval [95% CI], 1.463-2.013) or prefrail (OR 1.519; 95% CI, 1.296-1.779) were more likely to be discharged to inpatient rehabilitation. The final logistic regression model had a C-statistic of 0.63. Most of the patients discharged to inpatient rehabilitation were nonfrail (44.2%) and had moderate strokes (38.9%). Individuals who were frail and suffered a moderate (OR 0.78; 95% CI, 0.558-1.091) or severe stroke (OR 0.509; 95% CI, 0.358-0.721) were less likely to be discharged to an inpatient rehabilitation facility.
conclusionsA lack of a claims-based measure for prestroke functional ability makes it difficult to understand discharge decision-making patterns for individuals' poststroke. Prestroke frailty was found to have a significant effect on predicating inpatient rehabilitation discharge after an acute stroke when controlling for stroke severity, comorbidities, and age. Further investigation is warranted to examine differences in rehabilitation utilization based on frailty and to quantify the effect of rehabilitation on frailty status in individuals poststroke.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.