Evidence map›Paper›PMID 30922241›Full record

ArticleBMC cardiovascular disorders2019

Long-term survival and quality of life in Jehovah's witnesses after cardiac surgery: a case control study.

Pierre Wauthy, Charalampos Pierrakos, Louis Chebli, Redente Tortora

Registry-linked trialAbstract read
In one paragraph

Article in BMC cardiovascular disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03348072 (Comparative Study of Survival and Long-term Quality of Life After Cardiac Surgery in Patients Who Are Jehovah's Witnesses), which is not on this map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03348072 completednot on this map

Comparative Study of Survival and Long-term Quality of Life After Cardiac Surgery in Patients Who Are Jehovah's Witnesses

TypeobservationalSponsorPierre WauthyRan2016 to 2017Enrolled93ConditionsCardiac SurgeryArmsCardiac surgery
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pierre WauthyDepartment of Cardiac Surgery, CHU Brugmann, Place A van Gehuchten, 1020, Brussels, Belgium. pierre.wauthy@chu-brugmann.be.ORCID 0000-0002-5565-0719
Charalampos PierrakosIntensive Care Unit, CHU Brugmann, Université Libre de Bruxelles, Brussels, Belgium.
Louis ChebliDepartment of Cardiac Surgery, CHU Brugmann, Place A van Gehuchten, 1020, Brussels, Belgium.
Redente TortoraDepartment of Cardiac Surgery, CHU Brugmann, Place A van Gehuchten, 1020, Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe previously analyzed morbidity and mortality in Jehovah's Witnesses patients after cardiac surgery compared to control population patients. Patients who were Jehovah's Witnesses were operated in accordance with their philosophical convictions and in respect of their refusal of transfusions. We propose to assess long-term survival and quality of life in the patients of this preliminary study.

methodsWe contacted 31 adult Jehovah's Witnesses patients who underwent heart surgery at the Brugmann hospital between 1991 and 2012 and compared them to a control population of 62 patients that had no transfusion restriction, and matched them for sex, age at the time of intervention and the type of surgery performed. We compared long-term quality of life in both populations through the MacNew software, a validated instrument to assess quality of life of patients with cardiovascular disease. The long-term survival of patients was analyzed by Kaplan Meier curves.

resultsLong-term quality of life and survival do not appear different between the two groups. Patient evaluation by MacNew software shows comparable physical (p = 0.54), emotional (p = 0.12), social (p = 0.21) and global (p = 0.25) scores between the two populations. The analysis of the actuarial survival curves shows no differences in terms of long-term survival of these patients (p = 0.37).

conclusionsCardiac surgery in Jehovah's Witnesses can be performed with identical long-term quality of life and survival compared to surgery without blood transfusion restriction, if one follows rigorous blood conserving strategies.

trial registrationNCT03348072 . Retrospectively registered 16 November 2017.

Indexed as

Bloodless Medical and Surgical ProceduresBlood TransfusionCardiac Surgical ProceduresHealth Knowledge, Attitudes, PracticeQuality of LifeReligion and MedicineTreatment RefusalAgedBelgiumCase-Control StudiesFemaleHumansJehovah's WitnessesMaleMiddle AgedSurvivorsBleedingBlood transfusionCardiopulmonary bypassQuality of life

Identifiers

PMID30922241
PMCPMC6440098

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