ArticleBMC plant biology2019
The WRKY transcription factor GhWRKY27 coordinates the senescence regulatory pathway in upland cotton (Gossypium hirsutum L.).
Article in BMC plant biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 83 citations in OpenAlex.
- Genome-wide identification and functional analysis of the WRKY transcription factor family in Reynoutria japonica reveals its role in balancing growth and abiotic stress tolerance.BMC plant biology · 2026Article
- The Placenta Regulates Intrauterine Fetal Growth via Exosomal PPARγ.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Genome-wide identification and expression analysis of the WRKY gene family in Mikania micrantha.BMC genomics · 2025Article
- Genome-wide characterization ofFrontiers in plant science · 2025Article
- Gibberellin Positively Regulates Tomato Resistance toPlants (Basel, Switzerland) · 2024Article
- Dynamics of chromatin accessibility and genome wide control of desiccation tolerance in the resurrection plant Haberlea rhodopensis.BMC plant biology · 2023Article
- GhWRKY41 forms a positive feedback regulation loop and increases cotton defence response against Verticillium dahliae by regulating phenylpropanoid metabolism.Plant biotechnology journal · 2023Article
- The herbaceous peony transcription factor WRKY41a promotes secondary cell wall thickening to enhance stem strength.Plant physiology · 2023Article
- Transcriptomic and metabolomic analyses reveal the potential mechanism of waterlogging resistance in cotton (Frontiers in plant science · 2023Article
- Regulatory mechanism ofFrontiers in plant science · 2023Article
- A Comprehensive Gene Co-Expression Network Analysis Reveals a Role ofInternational journal of molecular sciences · 2022Article
- Role of WRKY Transcription Factors in Regulation of Abiotic Stress Responses in Cotton.Life (Basel, Switzerland) · 2022Review
- Identification of the WRKY Gene Family and Characterization of Stress-Responsive Genes inInternational journal of molecular sciences · 2022Article
- Characterization and expression analysis ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2022Article
- GhWRKY33 Interacts with GhTIFY10A to Synergistically Modulate Both Ageing and JA-Mediated Leaf Senescence inCells · 2022Article
- Characterization and Functional Analysis ofPlants (Basel, Switzerland) · 2022Article
- WRKY transcription factors (TFs): Molecular switches to regulate drought, temperature, and salinity stresses in plants.Frontiers in plant science · 2022Review
- QTL and candidate gene identification of the node of the first fruiting branch (NFFB) by QTL-seq in upland cotton (Gossypium hirsutum L.).BMC genomics · 2021Article
- A salicylic acid inducible mulberry WRKY transcription factor, MiWRKY53 is involved in plant defence response.Plant cell reports · 2021Article
- Comparative Transcriptome-Based Mining of Senescence-Related MADS, NAC, and WRKY Transcription Factors in the Rapid-Senescence Line DLS-91 ofInternational journal of molecular sciences · 2021Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPremature senescence can reduce the yield and quality of crops. WRKY transcription factors (TFs) play important roles during leaf senescence, but little is known about their ageing mechanisms in cotton.
resultsIn this study, a group III WRKY TF, GhWRKY27, was isolated and characterized. The expression of GhWRKY27 was induced by leaf senescence and was higher in an early-ageing cotton variety than in a non-early-ageing cotton variety. Overexpression of GhWRKY27 in Arabidopsis promoted leaf senescence, as determined by reduced chlorophyll content and elevated expression of senescence-associated genes (SAGs). Yeast two-hybrid (Y2H) and bimolecular fluorescence complementation (BiFC) assays showed that GhWRKY27 interacted with an MYB TF, GhTT2. Putative target genes of GhWRKY27 were identified via chromatin immunoprecipitation followed by sequencing (ChIP-seq). Yeast one-hybrid (Y1H) assay and electrophoretic mobility shift assay (EMSA) revealed that GhWRKY27 binds directly to the promoters of cytochrome P450 94C1 (GhCYP94C1) and ripening-related protein 2 (GhRipen2-2). In addition, the expression patterns of GhTT2, GhCYP94C1 and GhRipen2-2 were identified during leaf senescence. Transient dual-luciferase reporter assay indicated that GhWRKY27 could activate the expression of GhCYP94C1 and GhRipen2-2.
conclusionsOur work lays the foundation for further study of the functional roles of WRKY genes during leaf senescence in cotton. In addition, our data provide new insights into the senescence-associated mechanisms of WRKY genes in cotton.
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