Evidence map›Paper›PMID 30922213›Full record

ArticleBMC bioinformatics2019

PyCellBase, an efficient python package for easy retrieval of biological data from heterogeneous sources.

Daniel Perez-Gil, Francisco J Lopez, Joaquin Dopazo, Pablo Marin-Garcia, Augusto Rendon, Ignacio Medina

Abstract read
In one paragraph

Article in BMC bioinformatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniel Perez-GilGenomics England, London, UK.
Francisco J LopezGenomics England, London, UK.
Joaquin DopazoClinical Bioinformatics Area, Fundacion Progreso y Salud, Seville, Spain.
Pablo Marin-GarciaDepartment of Bioinformatics, Universidad Católica de Valencia, Valencia, Spain.
Augusto RendonGenomics England, London, UK.
Ignacio MedinaHPC Service, UIS, University of Cambridge, Cambridge, UK. im411@cam.ac.uk.ORCID http://orcid.org/0000-0003-0095-670X

Funding

Ministerio de Economía, Industria y Competitividad, Gobierno de España DTS16/00139Ministerio de Economía, Industria y Competitividad, Gobierno de España SAF2017-88908-R
6 · The paper itself

Abstract

backgroundBiological databases and repositories are incrementing in diversity and complexity over the years. This rapid expansion of current and new sources of biological knowledge raises serious problems of data accessibility and integration. To handle the growing necessity of unification, CellBase was created as an integrative solution. CellBase provides a centralized NoSQL database containing biological information from different and heterogeneous sources. Access to this information is done through a RESTful web service API, which provides an efficient interface to the data.

resultsIn this work we present PyCellBase, a Python package that provides programmatic access to the rich RESTful web service API offered by CellBase. This package offers a fast and user-friendly access to biological information without the need of installing any local database. In addition, a series of command-line tools are provided to perform common bioinformatic tasks, such as variant annotation. CellBase data is always available by a high-availability cluster and queries have been tuned to ensure a real-time performance.

conclusionPyCellBase is an open-source Python package that provides an efficient access to heterogeneous biological information. It allows to perform tasks that require a comprehensive set of knowledge resources, as for example variant annotation. Queries can be easily fine-tuned to retrieve the desired information of particular biological features. PyCellBase offers the convenience of an object-oriented scripting language and provides the ability to integrate the obtained results into other Python applications and pipelines.

Indexed as

Databases, FactualSoftwareComputational BiologyUser-Computer InterfaceAnnotationCellBaseDatabasePythonRepositoryRESTfulVariant

Identifiers

PMID30922213
PMCPMC6438028

What OpenQuestion holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.