Evidence map›Paper›PMID 30922148›Full record

Observational studyJournal of the International Association of Providers of AIDS Care

Effect of Health Insurance on Hepatitis C Sustained Virologic Response Rates to Sofosbuvir-Based Treatment Regimens in a South Florida Community Hospital.

Paula Eckardt, Jianli Niu, Angela Savage, Tara Griffin, Elizabeth Sherman

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of the International Association of Providers of AIDS Care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Paula Eckardt1 Division of Infectious Diseases, Memorial Physician Group, Hollywood, FL, USA.
Jianli Niu2 Office of Human Research, Memorial Healthcare System, Hollywood, FL, USA.ORCID 0000-0002-6131-9125
Angela Savage1 Division of Infectious Diseases, Memorial Physician Group, Hollywood, FL, USA.
Tara Griffin1 Division of Infectious Diseases, Memorial Physician Group, Hollywood, FL, USA.
Elizabeth Sherman1 Division of Infectious Diseases, Memorial Physician Group, Hollywood, FL, USA.
Memorial Healthcare System · USNova Southeastern University · US

Funding

University of Puerto Rico Mentoring Institute for HIV Mental Health ResearchR25MH083617 · NIMH · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI ZORRILLA, CARMEN D · 2008 to 2020
$3.7M
NIMH NIH HHS R25 MH083617
6 · The paper itself

Abstract

The high cost of direct-acting antiviral-based regimens raises concerns about the outcome of treatment in uninsured patients with chronic hepatitis C virus (HCV) infection. This study assessed the relationship between health insurance status and sustained virologic response (SVR) rates in a community hospital in South Florida. Sofosbuvir-based therapy was initiated in 82 patients, of which 73% were uninsured and 28 (34%) were HIV coinfection. The overall SVR rate for those tested was 98%. The SVR rates were similar between HCV mono- and HCV/HIV coinfected patients (96% versus 100%, P = .204). Uninsured patients, with access to patient assistance programs, had comparable SVR rates to insured patients (100% versus 95%, P = .131). However, there was a trend toward a higher rate of loss to follow-up in uninsured compared to insured patients (25% versus 9%, P = .116). Strategies specific to adherence to treatment for uninsured patients are needed to reduce rates of loss to follow-up.

Indexed as

Hospitals, CommunitySustained Virologic ResponseAntiviral AgentsDrug Therapy, CombinationFemaleFloridaHepacivirusHepatitis C, ChronicHIV InfectionsHumansInsurance CoverageInsurance, HealthMaleMedically UninsuredMiddle AgedRetrospective StudiesAntiviral AgentsSofosbuvirchronic hepatitis CHIVinsurance statussofosbuvir-based regimensSVR

Identifiers

PMID30922148
PMCPMC6748555
OpenAlexW2928862987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.