ArticlePhysics in medicine and biology2019
Assessment of histotripsy-induced liquefaction with diagnostic ultrasound and magnetic resonance imaging in vitro and ex vivo.
Article in Physics in medicine and biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 16 citations in OpenAlex.
- Histotripsy-Initiated Immune Response Synergizes with Chemotherapy in a Neuroblastoma Murine Model.Cancers · 2026Article
- Changes in bubble-cloud dissolution throughout the application of histotripsy pulses.Physical review applied · 2025Article
- Magnetic Resonance Imaging monitoring of histotripsy effects in agar phantom.Medical physics · 2025Article
- Accuracy and reproducibility of a single-pose image-to-robot registration method for mobile C-arm cone beam CT guided histotripsy.Journal of applied clinical medical physics · 2025Article
- Acoustic Cavitation Emissions Predict Near-complete/complete Histotripsy Treatment in Soft Tissues.Ultrasound in medicine & biology · 2025Article
- Overview of Therapeutic Ultrasound Applications and Safety Considerations: 2024 Update.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025Review
- Ultrasonic Nakagami imaging for automatically positioning and identifying the treated lesion induced by histotripsy.Ultrasonics sonochemistry · 2024Article
- Real-Time Passive Acoustic Mapping With Enhanced Spatial Resolution in Neuronavigation-Guided Focused Ultrasound for Blood-Brain Barrier Opening.IEEE transactions on bio-medical engineering · 2023Article
- An X-Ray C-Arm Guided Automatic Targeting System for Histotripsy.IEEE transactions on bio-medical engineering · 2023Article
- The histotripsy spectrum: differences and similarities in techniques and instrumentation.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2023Review
- Article
- Clot Degradation Under the Action of Histotripsy Bubble Activity and a Lytic Drug.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021Article
- Estimating the mechanical energy of histotripsy bubble clouds with high frame rate imaging.Physics in medicine and biology · 2021Article
- Assessment of Collaborative Robot (Cobot)-Assisted Histotripsy for Venous Clot Ablation.IEEE transactions on bio-medical engineering · 2021Article
- In vitro assessment of stiffness-dependent histotripsy bubble cloud activity in gel phantoms and blood clots.Physics in medicine and biology · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 1 institution in 2 countries.
Funding
Abstract
Histotripsy is a therapeutic ultrasound modality under development to liquefy tissue mechanically via bubble clouds. Image guidance of histotripsy requires both quantification of the bubble cloud activity and accurate delineation of the treatment zone. In this study, magnetic resonance (MR) and diagnostic ultrasound imaging were combined to assess histotripsy treatment in vitro and ex vivo. Mechanically ablative histotripsy pulses were applied to agarose phantoms or porcine livers. Bubble cloud emissions were monitored with passive cavitation imaging (PCI), and hyperechogenicity via plane wave imaging. Changes in the medium structure due to bubble activity were assessed with diagnostic ultrasound using conventional B-mode imaging and T
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.