ReviewRedox biology2019
Peroxisomal regulation of redox homeostasis and adipocyte metabolism.
Review in Redox biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 54 citations in OpenAlex.
- Peroxiredoxin II as a metabolic gatekeeper against aflatoxin BMycotoxin research · 2026Article
- Depot-dependent peroxisome response in the rat white adipose tissue under hypothyroidism.European journal of histochemistry : EJH · 2026Article
- A highly abundant circular RNA from the RMST locus plays a role in posterior fossa ependymoma pathogenesis.Brain pathology (Zurich, Switzerland) · 2026Article
- Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Perspectives.International journal of molecular sciences · 2026Review
- Transcriptome Analysis Reveals the Mechanism by which Probiotic Alleviate the Response of Juvenile American Shad (Alosa sapidissima) to High Temperatures.Probiotics and antimicrobial proteins · 2026Article
- Cross-scale design of abiotic-biotic interfaces for semi-artificial photosynthesis.Chemical science · 2026Review
- RNA-Binding Protein OsGRP3 Positively Regulates Rice Storability.Plants (Basel, Switzerland) · 2026Article
- Review
- The impact of zeaxanthin and lycopene on fatty acid beta-oxidation in isolated peroxisomes from frozen livers of obese rats.Frontiers in molecular biosciences · 2026Article
- Peroxisomal activity drives aggressive bladder cancer phenotypes and reveals erythorbic acid as a potential therapeutic modulator.Frontiers in oncology · 2026Article
- Article
- MCEE Promotes Intramuscular Fat Deposition in Pigs Through Regulating Mitochondrial Function.Animals : an open access journal from MDPI · 2025Article
- Astrocytic Inducible Nitric Oxide Synthase Upregulation Contributes to Chronic Below-Level Neuropathic Pain Following Spinal Cord Injury in Male Rats.European journal of pain (London, England) · 2025Article
- A charge reversal nano-assembly prevents hepatic steatosis by resolving inflammation and improving lipid metabolism.Bioactive materials · 2025Article
- Oxidative Stress and Redox Signaling in Gastric Cancer: From Mechanisms to Therapeutic Implications.Antioxidants (Basel, Switzerland) · 2025Review
- Exploring the Role of Peroxisome-Related Processes and Key Marker Genes in Sepsis: Insights Into Immune Dynamics and Therapeutic Potential.Journal of inflammation research · 2025Article
- The multiple roles of viral 3DVirulence · 2024Review
- 2-Hydroxylation is a chemical switch linking fatty acids to glucose-stimulated insulin secretion.The Journal of biological chemistry · 2024Article
- Regulation of Mitochondrial and Peroxisomal Metabolism in Female Obesity and Type 2 Diabetes.International journal of molecular sciences · 2024Review
- Mapping adipocyte interactome networks by HaloTag-enrichment-mass spectrometry.Biology methods & protocols · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Peroxisomes are ubiquitous cellular organelles required for specific pathways of fatty acid oxidation and lipid synthesis, and until recently their functions in adipocytes have not been well appreciated. Importantly, peroxisomes host many oxygen-consumption reactions and play a major role in generation and detoxification of reactive oxygen species (ROS) and reactive nitrogen species (RNS), influencing whole cell redox status. Here, we review recent progress in peroxisomal functions in lipid metabolism as related to ROS/RNS metabolism and discuss the roles of peroxisomal redox homeostasis in adipogenesis and adipocyte metabolism. We provide a framework for understanding redox regulation of peroxisomal functions in adipocytes together with testable hypotheses for developing therapies for obesity and the related metabolic diseases.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.