Evidence map›Paper›PMID 30921596›Full record

ArticleJournal of affective disorders2019

Allergies, asthma, and psychopathology in a nationally-representative US sample.

Kristen Kelly, Scott Ratliff, Briana Mezuk

Open access · greenAbstract read
In one paragraph

Article in Journal of affective disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Kristen KellyDepartment of Epidemiology, School of Public Health, University of Michigan, United States. Electronic address: kellykj@umich.edu.
Scott RatliffDepartment of Epidemiology, School of Public Health, University of Michigan, United States.
Briana MezukDepartment of Epidemiology, School of Public Health, University of Michigan, United States; Institute for Social Research, University of Michigan, United States.
University of Michigan · USUniversity of Mary · US

Funding

EPIDEMIOLOGY-- NATIONAL COMORBIDITY SURVEY REPLICATIONU01MH060220 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 1999 to 2010
$18.7M
University of Michigan Training Program in Genomic ScienceT32HG000040 · NHGRI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Sebastian Zoellner · 1995 to 2026
$16.4M
National Survey of American LifeU01MH057716 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JACKSON, JAMES SIDNEY · 1999 to 2009
$11.0M
NLAAS II: Unraveling Differences for Clinical ServicesU01MH062209 · NIMH · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI ALEGRIA, MARGARITA · 2000 to 2008
$10.6M
NATIONAL LATINO AND ASIAN AMERICAN STUDYU01MH062207 · NIMH · UNIVERSITY OF WASHINGTON · PI TAKEUCHI, DAVID T · 2000 to 2004
$7.2M
TREATMENT OF DEPRESSIONP01MH059876 · NIMH · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI ALEGRIA, MARGARITA · 1999 to 2003
$3.7M
Depression, inflammation, and diabetes: Exploring shared etiopathologyK01MH093642 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI MEZUK, BRIANA · 2012 to 2015
$689k
NHGRI NIH HHS T32 HG000040NIMH NIH HHS K01 MH093642NIMH NIH HHS P01 MH059876NIMH NIH HHS U01 MH057716NIMH NIH HHS U01 MH060220NIMH NIH HHS U01 MH062207NIMH NIH HHS U01 MH062209
6 · The paper itself

Abstract

backgroundSymptoms of depressed mood and anxiety have been associated with immune dysregulation and atopic disorders, however it is unclear whether this relationship spans other forms of psychopathology. The objective of this study was to use a large, population-based sample to examine the association between several common psychiatric conditions and two atopic disorders: seasonal allergies and asthma. This study also examined whether comorbidity between psychiatric disorders confounded the relationship between atopy and each psychiatric disorder.

methodsData come from the Comprehensive Psychiatric Epidemiology Surveys, a nationally-representative sample of US adults (N = 10,309). Lifetime history of major depressive disorder (MDD), generalized anxiety disorder (GAD), panic disorder (PD), and post-traumatic stress disorder (PTSD) was assessed using the Composite International Diagnostic Inventory. History of seasonal allergies and asthma were assessed by self-report. Weighted logistic regression was used to evaluate the association between allergies and asthma and psychopathology. Psychiatric comorbidities were also examined as potential confounders.

resultsApproximately 36.6% had a history of allergies and 11.5% a history of asthma. Seasonal allergies were positively associated with odds of MDD (Odds ratio (OR): 1.24, 95% Confidence Interval (CI): 1.06-1.46), GAD (OR: 1.54 (1.28-1.84)), PD (OR: 1.54 (1.24-1.91)), and PTSD (OR: 1.32 (1.09-1.59)). Asthma was not significantly associated with any psychiatric disorder. All significant associations persisted after adjustment for psychiatric comorbidities. LIMITATIONS: Limitations include self-reporting of atopic disorder status and of all disorder ages of onset.

conclusionsThis study confirms the association between MDD and PD and seasonal allergies, and extends this relationship to GAD and PTSD.

Indexed as

AdolescentAdultAgedAnxiety DisordersAsthmaFemaleHumansLogistic ModelsMajor Depressive DisorderMaleMiddle AgedOdds RatioPanic DisorderPsychopathologyRhinitis, Allergic, SeasonalSelf ReportAllergiesAnxietyAtopicDepressionPanicPTSD

Identifiers

PMID30921596
PMCPMC7671678
OpenAlexW2920863191

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.