Evidence map›Paper›PMID 30920503›Full record

ReviewGels (Basel, Switzerland)2017

Hydrogels for Biomedical Applications: Their Characteristics and the Mechanisms behind Them.

Qinyuan Chai, Yang Jiao, Xinjun Yu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Gels (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 339 papers.

0numbers the graph read from it
0cells of the map it votes in
339citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

339 citing papers in PubMed.

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279 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Qinyuan ChaiDepartment of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA. chaiqn@mail.uc.edu.
Yang JiaoDepartment of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA. jiaoyn@mail.uc.edu.
Xinjun YuDepartment of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA. yux3@mail.uc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogels are hydrophilic, three-dimensional networks that are able to absorb large quantities of water or biological fluids, and thus have the potential to be used as prime candidates for biosensors, drug delivery vectors, and carriers or matrices for cells in tissue engineering. In this critical review article, advantages of the hydrogels that overcome the limitations from other types of biomaterials will be discussed. Hydrogels, depending on their chemical composition, are responsive to various stimuli including heating, pH, light, and chemicals. Two swelling mechanisms will be discussed to give a detailed understanding of how the structure parameters affect swelling properties, followed by the gelation mechanism and mesh size calculation. Hydrogels prepared from natural materials such as polysaccharides and polypeptides, along with different types of synthetic hydrogels from the recent reported literature, will be discussed in detail. Finally, attention will be given to biomedical applications of different kinds of hydrogels including cell culture, self-healing, and drug delivery.

Indexed as

biomaterialscell culturedrug deliveryhydrogelsself-healing

Identifiers

PMID30920503
PMCPMC6318667

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.