Evidence map›Paper›PMID 30920454›Full record

ReviewCurrent opinion in rheumatology2019

Perioperative management of immunosuppression in patients with rheumatoid arthritis.

Michael D George, Joshua F Baker

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in rheumatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Ocular Clues in Musculoskeletal Disorders: A Narrative Review for Orthopaedic Specialists.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
    Review
  2. Article
  3. Article
  4. Posterior Only Reduction and Fixation of The Basilar Invagination and Atlantoaxial Dislocation Secondary to Severe Rheumatoid Arthritis: A Technical Note.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michael D GeorgeDivision of Rheumatology, University of Pennsylvania.
Joshua F BakerDivision of Rheumatology, University of Pennsylvania.
University of Pennsylvania · US

Funding

Risk and impact of infection resulting from treatment with chronic glucocorticoids in patients with rheumatoid arthritisK23AR073931 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI GEORGE, MICHAEL D. · 2018 to 2022
$873k
Adipokines as Biomarkers of Cachexia and High-Risk Rheumatoid ArthritisI01CX001703 · VA · PHILADELPHIA VA MEDICAL CENTER · PI BAKER, JOSHUA F. · 2019 to 2023
–
Body composition, bone structure, and joint damage in rheumatoid arthritisIK2CX000955 · VA · PHILADELPHIA VA MEDICAL CENTER · PI BAKER, JOSHUA F. · 2013 to 2017
–
CSRD VA I01 CX001703CSRD VA IK2 CX000955NIAMS NIH HHS K23 AR073931
6 · The paper itself

Abstract

purpose of reviewPatients with rheumatoid arthritis are at increased risk of infection after surgery. Recent literature has provided more data and updated guidelines to guide the management of immunosuppression in the perioperative period. RECENT

findingsStudies over the past few years have confirmed that patients with rheumatoid arthritis are at increased risk of infection after surgery. Patients treated with biologics are at greater risk of postoperative infection, but this risk might be explained by the comorbidities and greater disease severity often seen in these patients. Recent observational studies have suggested that interruption of biologic therapies before surgery may not be associated with better outcomes. Glucocorticoids, however, have consistently been found to be risk factors for infection. Recent guidelines from the American College of Rheumatology/American Association of Hip and Knee Surgeons recommend continuing conventional disease-modifying drugs and holding biologics for one dosing interval before surgery. SUMMARY: Prolonged interruption of conventional and biologic therapies before surgery does not appear to substantially reduce infection risk. Guidelines now recommend continuing conventional DMARDs and holding biologics for just one dosing interval before surgery. Glucocorticoids are strongly associated with the risk of postoperative infection and should be minimized before surgery.

Indexed as

Antirheumatic AgentsArthritis, RheumatoidHumansPerioperative CareRheumatologyAntirheumatic Agents

Identifiers

PMID30920454
PMCPMC6446585
OpenAlexW2927828396

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.