Evidence map›Paper›PMID 30920302›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2019

Effect of bacterial flagellin on thiamin uptake by human and mouse pancreatic acinar cells: inhibition mediated at the level of transcription of thiamin transporters 1 and 2.

Padmanabhan Srinivasan, Kasin Yadunandam Anandam, Vignesh Ramesh, Erica T Geltz, Hamid M Said

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Posttranscriptional regulation of thiamin transporter-1 expression by microRNA-200a-3p in pancreatic acinar cells.American journal of physiology. Gastrointestinal and liver physiology · 2020
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Padmanabhan SrinivasanDepartments of Medicine and Physiology/Biophysics, School of Medicine, University of California , Irvine, California.
Kasin Yadunandam AnandamDepartments of Medicine and Physiology/Biophysics, School of Medicine, University of California , Irvine, California.
Vignesh RameshDepartments of Medicine and Physiology/Biophysics, School of Medicine, University of California , Irvine, California.
Erica T GeltzDepartments of Medicine and Physiology/Biophysics, School of Medicine, University of California , Irvine, California.
Hamid M SaidDepartments of Medicine and Physiology/Biophysics, School of Medicine, University of California , Irvine, California.
Long Beach Medical Center · USUniversity of California, Irvine · US

Funding

INTESTINAL VITAMIN H UPTAKE--MOLECULAR/CELL REGULATIONR01DK058057 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI SAID, HAMID M · 2000 to 2019
$6.8M
Physiology/Pathophysiology of Vitamin B1 Transport in Pancreatic Acinar CellsR01AA018071 · NIAAA · UNIVERSITY OF CALIFORNIA-IRVINE · PI SAID, HAMID M · 2009 to 2023
$6.3M
Vitamin B1 (thiamin) transport in Alzheimer’s Disease: Role of microRNAs in regulating level of expression of its transporters (SLC19A2 & SLC19A3) in human brain cells and effect of hypoxiaR01DK056061 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI SAID, HAMID M · 1999 to 2024
$5.0M
Mechanism/Regulation of Intestinal Thiamin UptakeR37DK056061 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI SAID, HAMID M · 2009 to 2018
$3.6M
NIAAA NIH HHS R01 AA018071NIDDK NIH HHS R01 DK056061NIDDK NIH HHS R01 DK058057NIDDK NIH HHS R37 DK056061
6 · The paper itself

Abstract

Thiamin (vitamin B

Indexed as

Acinar CellsAnimalsBiological TransportCells, CulturedFlagellinHumansMembrane Transport ProteinsMicePancreas, ExocrinePromoter Regions, GeneticSp1 Transcription FactorThiamineToll-Like Receptor 5TranscriptomeFlagellinMembrane Transport ProteinsSLC19A2 protein, humanSlc19a2 protein, mouseSLC19A3 protein, humanSlc19a3 protein, mouseSp1 Transcription FactorThiamineToll-Like Receptor 5flagellinpancreatic acinar cellsthiamin uptakeTHTR-1THTR-2

Identifiers

PMID30920302
PMCPMC6620585
OpenAlexW2930733657

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.