Evidence map›Paper›PMID 30920223›Full record

ArticleJournal of the American Chemical Society2019

Disparate Catalytic Scaffolds for Atroposelective Cyclodehydration.

Yongseok Kwon, Junqi Li, Jolene P Reid, Jennifer M Crawford, Roxane Jacob, Matthew S Sigman, F Dean Toste, Scott J Miller

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Recent advances in organocatalytic atroposelective reactions.Beilstein journal of organic chemistry · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Catalytic Asymmetric Synthesis of AtropisomericThe Journal of organic chemistry · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Asymmetric Synthesis of Axially Chiral C-N Atropisomers.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022
    Review
  18. Article
  19. Open questions on the transfer of chirality.Communications chemistry · 2021
    Article
  20. Data Science Meets Physical Organic Chemistry.Accounts of chemical research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yongseok KwonDepartment of Chemistry , Yale University , New Haven , Connecticut 06520-8107 , United States.
Junqi LiDepartment of Chemistry , Yale University , New Haven , Connecticut 06520-8107 , United States.ORCID 0000-0003-0336-2544
Jolene P ReidDepartment of Chemistry , University of Utah , 315 South 1400 East , Salt Lake City , Utah 84112 , United States.
Jennifer M CrawfordDepartment of Chemistry , University of Utah , 315 South 1400 East , Salt Lake City , Utah 84112 , United States.
Roxane JacobDepartment of Chemistry , University of California, Berkeley , Berkeley , California 94720 , United States.
Matthew S SigmanDepartment of Chemistry , University of Utah , 315 South 1400 East , Salt Lake City , Utah 84112 , United States.ORCID 0000-0002-5746-8830
F Dean TosteDepartment of Chemistry , University of California, Berkeley , Berkeley , California 94720 , United States.ORCID 0000-0001-8018-2198
Scott J MillerDepartment of Chemistry , Yale University , New Haven , Connecticut 06520-8107 , United States.ORCID 0000-0001-7817-1318

Funding

Using Numerical Analysis Tools to Design and Study Chiral CatalystsR01GM121383 · NIGMS · UNIVERSITY OF UTAH · PI MILLER, SCOTT J, SIGMAN, MATTHEW S · 2017 to 2020
$1.9M
NIGMS NIH HHS R01 GM121383
6 · The paper itself

Abstract

Catalysts that control stereochemistry are prized tools in chemical synthesis. When an effective catalyst is found, it is often explored for other types of reactions, frequently under the auspices of different mechanisms. As successes mount, a unique catalyst scaffold may become viewed as "privileged". However, the mechanistic hallmarks of privileged catalysts are not easily enumerated or readily generalized to genuinely different classes of reactions or substrates. We explored the concept of scaffold uniqueness with two catalyst types for an unusual atropisomer-selective cyclodehydration: (a) C

Indexed as

CatalysisDensity Functional TheoryPhosphoric AcidsStereoisomerismphosphoric acidPhosphoric Acids

Identifiers

PMID30920223
PMCPMC6482060

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.