ArticlePhysiological reports2019
Variability in human plasma volume responses during high-altitude sojourn.
Article in Physiological reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of hypoxic high-intensity interval training on cardiorespiratory fitness, body composition, and cardiometabolic outcomes in non-clinical populations: a systematic review and meta-analysis with an age-related evidence distribution assessment.BMC sports science, medicine & rehabilitation · 2026Pooled it
- The relationship between hemoglobin andPloS one · 2023Pooled it
- Health-Related Physical Fitness Associated With Hypertension Risk in Adults Living in Sub-Plateau Environments.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- HRV and blood parameters for assessing the physiological functioning of cyclists during long-distance rides across different altitudes.Frontiers in physiology · 2025Article
- Removal of the influence of plasma volume fluctuations for the athlete biological passport and stability of haematological variables in active women taking oral contraception.Drug testing and analysis · 2022Article
- Wearable Sensors and Machine Learning for Hypovolemia Problems in Occupational, Military and Sports Medicine: Physiological Basis, Hardware and Algorithms.Sensors (Basel, Switzerland) · 2022Review
- Altitude and Erythropoietin: Comparative Evaluation of Their Impact on Key Parameters of the Athlete Biological Passport: A Review.Frontiers in sports and active living · 2022Review
- Fifteen days of moderate normobaric hypoxia does not affect mitochondrial function, and related genes and proteins, in healthy men.European journal of applied physiology · 2021Article
- Regulation of plasma volume in male lowlanders during 4 days of exposure to hypobaric hypoxia equivalent to 3500 m altitude.The Journal of physiology · 2021Article
- Spleen Contraction During Sudden Eupneic Hypoxia Elevates Hemoglobin Concentration.Frontiers in physiology · 2021Article
- Heterogeneity of Hematological Response to Hypoxia and Short-Term or Medium-Term Bed Rest.Frontiers in physiology · 2021Article
- The Influence of Training Load on Hematological Athlete Biological Passport Variables in Elite Cyclists.Frontiers in sports and active living · 2021Article
- Variability in human plasma volume responses during high-altitude sojourn.Physiological reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
When sea-level (SL) residents rapidly ascend to high altitude (HA), plasma volume (PV) decreases. A quantitative model for predicting individual %∆PV over the first 7 days at HA has recently been developed from the measurements of %∆PV in 393 HA sojourners. We compared the measured %∆PV with the %∆PV predicted by the model in 17 SL natives living 21 days at HA (4300 m). Fasting hematocrit (Hct), hemoglobin (Hb) and total circulating protein (TCP) concentrations at SL and on days 2, 7, 13, and 19 at HA were used to calculate %∆TCP and %∆PV. Mean [95%CI] measured %∆PV on HA2, 7, 13 and 19 was -2.5 [-8.2, 3.1], -11.0 [-16.6, -5.5], -11.7 [-15.9, -7.4], and -16.8 [-22.2, -11.3], respectively. %∆PV and %∆TCP were positively correlated (P < 0.001) at HA2, 7, 13, and 19 (r
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.