Evidence map›Paper›PMID 30919955›Full record

ArticleEuropean journal of immunology2019

Recruitment of hepatic macrophages from monocytes is independent of IL-4Rα but is associated with ablation of resident macrophages in schistosomiasis.

Marion Rolot, Annette M Dougall, Justine Javaux, François Lallemand, Bénédicte Machiels, Philippe Martinive, Laurent Gillet, Benjamin G Dewals

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in European journal of immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Exploring CD169Vaccines · 2025
    Review
  3. Targeting hepatic macrophages for non-alcoholic fatty liver disease therapy.Frontiers in cell and developmental biology · 2024
    Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Enhanced Proliferation of Ly6CJournal of immunology (Baltimore, Md. : 1950) · 2021
    Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Marion RolotImmunology-Vaccinology, Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine - FARAH, University of Liège, Liège, Belgium.
Annette M DougallImmunology-Vaccinology, Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine - FARAH, University of Liège, Liège, Belgium.
Justine JavauxImmunology-Vaccinology, Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine - FARAH, University of Liège, Liège, Belgium.
François LallemandDepartment of Radiotherapy, University Hospital Liège, Liège, Belgium.
Bénédicte MachielsImmunology-Vaccinology, Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine - FARAH, University of Liège, Liège, Belgium.
Philippe MartiniveDepartment of Radiotherapy, University Hospital Liège, Liège, Belgium.
Laurent GilletImmunology-Vaccinology, Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine - FARAH, University of Liège, Liège, Belgium.
Benjamin G DewalsImmunology-Vaccinology, Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine - FARAH, University of Liège, Liège, Belgium.ORCID 0000-0003-1497-0799
University of Liège · BE

Funding

NIAID NIH HHS HHSN272201000005I
6 · The paper itself

Abstract

Alternatively activated Mφs (AAMφ) accumulate in hepatic granulomas during schistosomiasis and have been suggested to originate in the bone marrow. What is less understood is how these Mφ responses are regulated after S. mansoni infection. Here, we investigated the role of IL-4 receptor α-chain (IL-4Rα)-signalling in the dynamics of liver Mφ responses. We observed that IL-4Rα signalling was dispensable for the recruitment of Ly6C

Indexed as

Ablation TechniquesAnimalsDisease Models, AnimalFemaleGranulomaHumansInterleukin-4 Receptor alpha SubunitKupffer CellsLiverMacrophage ActivationMacrophagesMiceMice, Inbred BALB CMice, KnockoutReceptors, Cell SurfaceSchistosoma mansoniIl4ra protein, mouseInterleukin-4 Receptor alpha SubunitReceptors, Cell Surfacelivermonocytesmouse modelMφschistosomiasis

Identifiers

PMID30919955
OpenAlexW2931504371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.