Evidence map›Paper›PMID 30919598›Full record

ArticleJournal of diabetes investigation2019

Rho-associated, coiled-coil-containing protein kinase 1 as a new player in the regulation of hepatic lipogenesis.

Takafumi Miyamoto, Takashi Matsuzaka, Hitoshi Shimano

Abstract readComment
In one paragraph

Article in Journal of diabetes investigation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Takafumi MiyamotoDepartment of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Tsukuba-City, Ibaraki, Japan.ORCID 0000-0001-9363-2864
Takashi MatsuzakaDepartment of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Tsukuba-City, Ibaraki, Japan.
Hitoshi ShimanoDepartment of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, Tsukuba-City, Ibaraki, Japan.

Funding

Grant-in-Aid for Scientific Research on Innovative Areas 18H04854The Leading Initiative for Excellent Young Researchers 16811470
6 · The paper itself

Abstract

Rho-associated, coiled-coil-containing protein kinase 1 might have applications as a potential therapeutic target for the treatment of non-alcoholic fatty liver disease.

Indexed as

Overnutritionrho-Associated KinasesAMP-Activated Protein KinasesHumansLipogenesisLiverAMP-Activated Protein Kinasesrho-Associated Kinases

Identifiers

PMID30919598
PMCPMC6717821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.