ReviewBioEssays : news and reviews in molecular, cellular and developmental biology2019
Stress-Induced Evolutionary Innovation: A Mechanism for the Origin of Cell Types.
Review in BioEssays : news and reviews in molecular, cellular and developmental biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed.
- Review
- Biology Needs Philosophy, But What Philosophy?Bioscience · 2026Review
- Review
- Mechanisms driving resistance to oxidative stress during endometrial stromal cell decidualization†.Biology of reproduction · 2026Review
- Environmentally dependent developmental induction as a potential driver of heart evolution.The Journal of experimental biology · 2026Review
- Reframing the significance of menstruation: evolutionary insights from an organismal-relational perspective.History and philosophy of the life sciences · 2025Article
- Evolutionary trends in the emergence of skeletal cell types.Evolution letters · 2025Article
- Cryptic genetic variation in brain gene expression precedes the evolution of cannibalism in spadefoot toad tadpoles.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Plasticity and the evolution of group-level regulation of cellular differentiation in the volvocine algae.Proceedings. Biological sciences · 2025Article
- Functional analysis of regA paralog rlsD in Volvox carteri.The Plant journal : for cell and molecular biology · 2024Article
- Stress sharing as cognitive glue for collective intelligences: A computational model of stress as a coordinator for morphogenesis.Biochemical and biophysical research communications · 2024Article
- Review
- Reconciling continuous and discrete models of C4 and CAM evolution.Annals of botany · 2023Article
- An RFX transcription factor regulates ciliogenesis in the closest living relatives of animals.Current biology : CB · 2023Article
- High-Quality Chromosome-Level Genome Assembly of the Corsac Fox (International journal of molecular sciences · 2023Article
- The Genetics of Fitness Reorganization during the Transition to Multicellularity: The VolvocineGenes · 2023Review
- Pleiotropic Functions of Nitric Oxide Produced by Ascorbate for the Prevention and Mitigation of COVID-19: A Revaluation of Pauling's Vitamin C Therapy.Microorganisms · 2023Review
- Snake venom gene expression is coordinated by novel regulatory architecture and the integration of multiple co-opted vertebrate pathways.Genome research · 2022Article
- Co-option of stress mechanisms in the origin of evolutionary novelties.Evolution; international journal of organic evolution · 2022Article
- Inflammation and convergent placenta gene co-option contributed to a novel reproductive tissue.Current biology : CB · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Understanding the evolutionary role of environmentally induced phenotypic variation (i.e., plasticity) is an important issue in developmental evolution. A major physiological response to environmental change is cellular stress, which is counteracted by generic stress reactions detoxifying the cell. A model, stress-induced evolutionary innovation (SIEI), whereby ancestral stress reactions and their corresponding pathways can be transformed into novel structural components of body plans, such as new cell types, is described. Previous findings suggest that the cell differentiation cascade of a cell type critical to pregnancy in humans, the decidual stromal cell, evolved from a cellular stress reaction. It is hypothesized that the stress reaction in these cells was elicited ancestrally via inflammation caused by embryo attachment. The present study proposes that SIEI is a distinct form of plasticity-based evolutionary change leading to the origin of novel structures rather than adaptive transformation of pre-existing characters.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.