ArticleEndocrine2019
High-intensity focused ultrasound (HIFU) for benign thyroid nodules: 2-year follow-up results.
Article in Endocrine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Efficacy of HIFU for the treatment of benign thyroid nodules: a systematic review and meta-analysis.European radiology · 2024Pooled it
- Efficacy of thermal ablation in benign non-functioning solid thyroid nodule: A systematic review and meta-analysis.Endocrine · 2020Pooled it
- Model-Optimizing Radiofrequency Parameters of 3D Finite Element Analysis for Ablation of Benign Thyroid Nodules.Bioengineering (Basel, Switzerland) · 2023Article
- [Clinical Approach for Thyroid Radiofrequency Ablation].Journal of the Korean Society of Radiology · 2023Review
- Effects of Regional and General Anesthesia on the Therapeutic Outcome of Benign Thyroid Nodules Treated with High Intensity Focused Ultrasound (HIFU).World journal of surgery · 2022Article
- Correlation and agreement between superb micro-vascular imaging and contrast-enhanced ultrasound for assessing radiofrequency ablation treatment of thyroid nodules: a preliminary study.BMC medical imaging · 2021Article
- Efficacy on radiofrequency ablation according to the types of benign thyroid nodules.Scientific reports · 2021Article
- Performance of Contrast-Enhanced Ultrasound in Thyroid Nodules: Review of Current State and Future Perspectives.Cancers · 2021Review
- The Role of CEUS in the Evaluation of Thyroid Cancer: From Diagnosis to Local Staging.Journal of clinical medicine · 2021Review
- Conspicuousness and recurrence related factors of ultrasound-guided microwave ablation in the treatment of benign thyroid nodules.BMC surgery · 2021Article
- Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules.Saudi medical journal · 2021Article
- Occupational exposure and radiobiological risk from thyroid radioiodine therapy in Saudi Arabia.Scientific reports · 2021Article
- Focus on radioiodine-131 biokinetics: the influence of methylprednisolone on intratherapeutic effective half-life ofEndocrine · 2021Article
- RFA and benign thyroid nodules: Review of the current literature.Laryngoscope investigative otolaryngology · 2021Review
- Long-Term Outcomes of Thermal Ablation for Benign Thyroid Nodules: The Issue of Regrowth.International journal of endocrinology · 2021Review
- Update of Radiofrequency Ablation for Treating Benign and Malignant Thyroid Nodules. The Future Is Now.Frontiers in endocrinology · 2021Review
- 2020 European Thyroid Association Clinical Practice Guideline for the Use of Image-Guided Ablation in Benign Thyroid Nodules.European thyroid journal · 2020Article
- The current state and future perspectives of high intensity focused ultrasound (HIFU) ablation for benign thyroid nodules.Gland surgery · 2020Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHigh-intensity focused ultrasound (HIFU) is the last introduced thermal treatment of thyroid nodules. Here we evaluated the results at 24 months after HIFU.
methodsSince 2016, HIFU was considered as a therapeutic option at our institute in patients with benign thyroid nodules presenting local symptoms. We searched in our database all patients who had undergone thyroid HIFU and selected for the study only cases followed-up for at least 24 months after the treatment. Volume reduction rate (VRR) was evaluated. A reduction above 50% defined the success of HIFU.
resultsThirty-one nodules of 31 patients (24 females and 7 males, median age 67 years) with median major diameter from 17 to 34 mm and estimated nodule volume of 5.48 mL were included. HIFU was performed with median power of 42 W/site (interquartile range 25-45) and median energy of 263 J/site (interquartile range 225-273). Median duration of the procedure was 6 min (interquartile range 5-7). At 2 years after HIFU, nodule volume was significantly (p < 0.0001) lower (i.e., 3.40 mL) with VRR of 43.3%, and 26 (83.9%) lesions were reduced. A reduction by at least 50% was observed at 6, 12, and 24 months in 2 (6.4%), 5 (16.1%), and 7 (22.5%) nodules, respectively. Visual analog score showed a significant improvement (p < 0.0001). No complications were recorded.
conclusionsA reduction of benign thyroid nodule by more than 40% could be reached within 1 year by HIFU. Given the non-significant size increase of some lesions later, a larger study with a longer follow-up is necessary.
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