ArticleProtoplasma2019
SlNAC2 overexpression in Arabidopsis results in enhanced abiotic stress tolerance with alteration in glutathione metabolism.
Article in Protoplasma, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 54 citations in OpenAlex.
- Tomato NAC2-DREB2 module fine-tunes saline-alkali stress sensitivity via modulation of melatonin biosynthesis and ROS homeostasis.Horticulture research · 2026Article
- SlDCD and SlLCD increased the salt tolerance in tomato seedlings by enhancing antioxidant and photosynthesis capacity.Plant cell reports · 2025Article
- Transcriptome and WGCNA analysis revealed the molecular mechanism of drought resistance in new sugarcane varieties.Frontiers in plant science · 2025Article
- The Spartina alterniflora genome sequence provides insights into the salt-tolerance mechanisms of exo-recretohalophytes.Plant biotechnology journal · 2024Article
- CsSHMT3 gene enhances the growth and development in cucumber seedlings under salt stress.Plant molecular biology · 2024Article
- Genome-wide analysis of the Tritipyrum NAC gene family and the response of TtNAC477 in salt tolerance.BMC plant biology · 2024Article
- Antioxidants of Non-Enzymatic Nature: Their Function in Higher Plant Cells and the Ways of Boosting Their Biosynthesis.Antioxidants (Basel, Switzerland) · 2023Review
- Review of the Mechanisms by Which Transcription Factors and Exogenous Substances Regulate ROS Metabolism under Abiotic Stress.Antioxidants (Basel, Switzerland) · 2022Review
- Article
- A Transcription FactorInternational journal of molecular sciences · 2022Article
- Over-Expression of an R2R3 MYB Gene,International journal of molecular sciences · 2022Article
- BcGR1.1, a Cytoplasmic Localized Glutathione Reductase, Enhanced Tolerance to Copper Stress inAntioxidants (Basel, Switzerland) · 2022Article
- ThePhysiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- Knockout of Auxin Response Factor SlARF4 Improves Tomato Resistance to Water Deficit.International journal of molecular sciences · 2021Article
- Article
- Transcriptome and Co-expression Network Analyses Reveal Differential Gene Expression and Pathways in Response to Severe Drought Stress in Peanut (Frontiers in genetics · 2021Article
- Deciphering hydrogen peroxide-induced signalling towards stress tolerance in plants.3 Biotech · 2019Review
- Regulation of Ascorbate-Glutathione Pathway in Mitigating Oxidative Damage in Plants under Abiotic Stress.Antioxidants (Basel, Switzerland) · 2019Review
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant NAC (NAM, ATAF, and CUC) transcription factors (TF) have important roles to play in abiotic stress responses through activation of a battery of functional genes/transcriptional regulators responsible for stress tolerance. Here we report the cloning of a novel Solanum lycopersicum L., NAC2 TF having 960 nucleotides long CDS (GenBank: KT740994.1). Phylogenetic analysis depicted the similarity of SlNAC2 to other orthologs. SlNAC2 was overexpressed in Arabidopsis thaliana to assess and characterize its role in plant abiotic stress responses. The transgenic events were first confirmed by genomic DNA PCR and qRT PCR; then the T3 generation plants were used for stress assays. Soil stress assay depicted better survivability of the transgenic plants under both salt (NaCl) and drought (PEG) stress. The transgenic plants showed enhanced endurance; with better antioxidative response, reduced accumulation of reactive oxygen species (ROS) molecules and better retention of water in tissue. This study for the very first time analyzed the different stakeholders of the glutathione metabolism in SlNAC2 overexpressing transgenic lines on exposure to both salinity and PEG stress. The expression of the two genes (ɤ-ECS, GS) responsible for glutathione biosynthesis increased with SlNAC2 overexpression. Further glutathione reductase responsible for reduction of glutathione disulfide (GSSG) to glutathione (GSH) also increased significantly which suggested the regulation of glutathione metabolism as a mechanism for the osmotic stress tolerance conferred to plants upon NAC overexpression.
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