Evidence map›Paper›PMID 30919008›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2019

Pinacidil, a KATP channel opener, stimulates cardiac Na

Keisuke Iguchi, Masao Saotome, Kanna Yamashita, Prottoy Hasan, Miyuki Sasaki, Yuichiro Maekawa, Yasuhide Watanabe

Abstract read
PubMed Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. KAmerican journal of physiology. Cell physiology · 2022
    Review
  4. Functional Regulation of KFrontiers in pharmacology · 2022
    Review
  5. Article
  6. Article
  7. Cardiac NaThe journal of physiological sciences : JPS · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Keisuke IguchiDepartment of Internal Medicine III (Cardiology), Hamamatsu University School of Medicine, Hamamatsu, 431-3192, Japan.
Masao SaotomeDepartment of Internal Medicine III (Cardiology), Hamamatsu University School of Medicine, Hamamatsu, 431-3192, Japan.
Kanna YamashitaDivision of Pharmacological Science, Department of Health Science, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu, 431-3192, Japan.
Prottoy HasanDepartment of Internal Medicine III (Cardiology), Hamamatsu University School of Medicine, Hamamatsu, 431-3192, Japan.
Miyuki SasakiDivision of Pharmacological Science, Department of Health Science, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu, 431-3192, Japan.
Yuichiro MaekawaDepartment of Internal Medicine III (Cardiology), Hamamatsu University School of Medicine, Hamamatsu, 431-3192, Japan.
Yasuhide WatanabeDivision of Pharmacological Science, Department of Health Science, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu, 431-3192, Japan. w-yasu@hama-med.ac.jp.
Hamamatsu University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pinacidil, a nonselective ATP-sensitive K

Indexed as

Cyclic GMPCyclic GMP-Dependent Protein KinasesNitric OxideAnimalsAntioxidantsGuinea PigsHeart VentriclesKATP ChannelsMyocytes, CardiacPatch-Clamp TechniquesPinacidilSignal TransductionSodium-Calcium ExchangerStimulation, ChemicalAntioxidantsCyclic GMPCyclic GMP-Dependent Protein KinasesKATP ChannelsNitric OxidePinacidilSodium-Calcium ExchangerCardiac myocytesNa+/Ca2+ exchange current (INCX)Nonselective KATP channel openerPatch-clamp techniquePinacidil

Identifiers

PMID30919008
OpenAlexW2923590466

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.