Evidence map›Paper›PMID 30918961›Full record

ArticleNeuro-oncology2019

Targeted copy number analysis outperforms histologic grading in predicting patient survival for WHO grades II/III IDH-mutant astrocytomas.

Patrick J Cimino, Eric C Holland

Abstract readComparative Study
In one paragraph

Article in Neuro-oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Clinical outcomes and management ofNeuro-oncology practice · 2025
    Article
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  6. Article
  7. Article
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  9. Review
  10. Article
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  13. Article
  14. Current issues in molecular biology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Patrick J CiminoDepartment of Pathology, Division of Neuropathology, University of Washington School of Medicine, Seattle, Washington.
Eric C HollandDivision of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington.

Funding

THERAPEUTIC EFFECTS OF INTRA-NASAL INSULIN DETEMIRP50AG005136 · NIA · UNIVERSITY OF WASHINGTON · PI JAYADEY, SUMAN · 1985 to 2019
$57.2M
Furthering scientific understanding of mechanisms underlying resilience to the effects of AD pathology by incorporating state of the art quantification of gliosis, inflammation, & synaptic toxicityU01AG006781 · NIA · UNIVERSITY OF WASHINGTON · PI CRANE, PAUL K, LARSON, ERIC B · 1986 to 2020
$39.3M
NIA NIH HHS P50 AG005136NIA NIH HHS U01 AG006781
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA Copy Number VariationsMutationAstrocytomaBiomarkers, TumorBrain NeoplasmsCohort StudiesHumansIsocitrate DehydrogenaseNeoplasm GradingSurvival RateWorld Health OrganizationBiomarkers, TumorIDH1 protein, humanIDH2 protein, humanIsocitrate DehydrogenaseastrocytomabiomarkersIDHisocitrate dehydrogenasemolecular profiling

Identifiers

PMID30918961
PMCPMC6556841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.