Evidence map›Paper›PMID 30918806›Full record

ArticleInternational journal of ophthalmology2019

Comparison of the meibomian gland dysfunction in patients with chronic ocular graft-versus-host disease and Sjögren's syndrome.

Won Choi, Jun Young Ha, Ying Li, Jung Han Choi, Yong Sok Ji, Kyung Chul Yoon

Open access · goldAbstract read
In one paragraph

Article in International journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Meibomian gland atrophy in children with allergic conjunctivitis.International journal of ophthalmology · 2025
    Article
  5. Meibomian Gland Dysfunction Clinical Practice Guidelines.Japanese journal of ophthalmology · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Update on ocular graft-versus-host disease.Indian journal of ophthalmology · 2021
    Review
  11. Article
  12. Article
  13. New approaches for diagnosis of dry eye disease.International journal of ophthalmology · 2019
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Won ChoiDepartment of Ophthalmology and Research Institute of Medical Sciences, Chonnam National University Medical School and Hospital, Gwangju 501-757, South Korea.
Jun Young HaDepartment of Ophthalmology and Research Institute of Medical Sciences, Chonnam National University Medical School and Hospital, Gwangju 501-757, South Korea.
Ying LiDepartment of Ophthalmology and Research Institute of Medical Sciences, Chonnam National University Medical School and Hospital, Gwangju 501-757, South Korea.
Jung Han ChoiDepartment of Ophthalmology and Research Institute of Medical Sciences, Chonnam National University Medical School and Hospital, Gwangju 501-757, South Korea.
Yong Sok JiDepartment of Ophthalmology and Research Institute of Medical Sciences, Chonnam National University Medical School and Hospital, Gwangju 501-757, South Korea.
Kyung Chul YoonDepartment of Ophthalmology and Research Institute of Medical Sciences, Chonnam National University Medical School and Hospital, Gwangju 501-757, South Korea.
Chonnam National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the abnormalities in the meibomian gland in patients with dry eye disease (DED) associated with chronic ocular graft-versus-host disease (coGVHD) in comparison with Sjögren's syndrome (SS), a major form of aqueous deficient DED and meibomian gland dysfunction (MGD), a common cause of evaporative DED.

methodsA total 135 eyes of 135 subjects included in this study: patients with DED associated with coGVHD (

resultsThe coGVHD group showed significantly higher meiboscore, MES, and MQS than the other 3 groups (all

conclusionPatients with DED associated with coGVHD show poorer gland morphology and worse gland function than other types of DED. In addition, meibomian gland damage is not only associated with ocular surface damage but also disease severity of coGVHD.

Indexed as

chronic ocular graft-versus-host diseasedry eye diseasemeibographymeibomian gland dysfunctionSjögren's syndrome

Identifiers

PMID30918806
PMCPMC6423382
OpenAlexW2940909897

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.