Evidence map›Paper›PMID 30918721›Full record

ArticleCardiology research and practice2019

Comparison of Echocardiographic and Electrocardiographic Mapping for Cardiac Resynchronisation Therapy Optimisation.

Helder Pereira, Tom A Jackson, Simon Claridge, Jonathan M Behar, Cheng Yao, Benjamin Sieniewicz, Justin Gould, Bradley Porter, Baldeep Sidhu, Jaswinder Gill and 2 more

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiology research and practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Non-invasive three-dimensional electrical activation mapping to predict cardiac resynchronization therapy response: site of latest left ventricular activation relative to pacing site.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  2. Review
  3. Article
  4. Review
  5. Clinical Utility of Body Surface Potential Mapping in CRT Patients.Arrhythmia & electrophysiology review · 2021
    Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Helder PereiraDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.ORCID 0000-0001-9377-5662
Tom A JacksonDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Simon ClaridgeDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Jonathan M BeharDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Cheng YaoMedtronic Ltd, UK.
Benjamin SieniewiczDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Justin GouldDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Bradley PorterDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Baldeep SidhuDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Jaswinder GillCardiovascular Department, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Steven NiedererDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Christopher A RinaldiDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.

Funding

Department of Health II-LB-1116-20001Wellcome Trust
6 · The paper itself

Abstract

study hypothesisWe sought to investigate the association between echocardiographic optimisation and ventricular activation time in cardiac resynchronisation therapy (CRT) patients, obtained through the use of electrocardiographic mapping (ECM). We hypothesised that echocardiographic optimisation of the pacing delay between the atrial and ventricular leads-atrioventricular delay (AVD)-and the delay between ventricular leads-interventricular pacing interval (VVD)-would correlate with reductions in ventricular activation time.

backgroundOptimisation of AVD and VVD may improve CRT patient outcome. Optimal delays are currently set based on echocardiographic indices; however, acute studies have found that reductions in bulk ventricular activation time correlate with improvements in acute haemodynamic performance. MATERIALS AND

methodsTwenty-one patients with established CRT criteria were recruited. After implantation, patients underwent echo-guided optimisation of the AVD and VVD. During this procedure, the participants also underwent noninvasive ECM. ECM maps were constructed for each AVD and VVD. ECM maps were analysed offline. Total ventricular activation time (TVaT) and a ventricular activation time index (VaT

resultsEchocardiographic programming optimisation was not associated with the greatest reductions in biventricular activation time (VaT

conclusionsEAM-guided programming optimisation may achieve superior fusion of activation wave fronts leading to improvements in CRT response.

Identifiers

PMID30918721
PMCPMC6409049

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