ArticleFood science & nutrition2019
Protective effect of walnut on d-galactose-induced aging mouse model.
Article in Food science & nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 49 citations in OpenAlex.
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- Optimization of ultrasonic-assisted extraction of total flavonoids fromRSC advances · 2024Article
- Walnut oil: a promising nutraceutical in reducing oxidative stress and improving cholinergic activity in anToxicology research · 2024Article
- Can daily consumption of enriched fatty acids diet be effective in improving metabolic syndrome? An attractive paradox for walnut kernel.Food science & nutrition · 2024Review
- Integrated metabolomic and transcriptomic dynamic profiles of endopleura coloration during fruit maturation in three walnut cultivars.BMC plant biology · 2024Article
- Chelidonic acid abrogates oxidative stress and memory dysfunction in experimental aging rats.Turkish journal of biology = Turk biyoloji dergisi · 2024Article
- Pharmacotherapeutic potential of walnut (Juglans spp.) in age-related neurological disorders.IBRO neuroscience reports · 2023Review
- A comparative study of anti-aging effects ofJournal of clinical and translational research · 2022Article
- Article
- Walnut Prevents Cognitive Impairment by Regulating the Synaptic and Mitochondrial Dysfunction via JNK Signaling and Apoptosis Pathway in High-Fat Diet-Induced C57BL/6 Mice.Molecules (Basel, Switzerland) · 2022Article
- Protective Effects of Water Extract ofVeterinary sciences · 2021Article
- Oral administration of D-galactose increases brain tricarboxylic acid cycle enzymes activities in Wistar rats.Metabolic brain disease · 2021Article
- Investigating walnut consumption and cognitive trajectories in a representative sample of older US adults.Public health nutrition · 2021Observational
- Calcium Dobesilate Reverses Cognitive Deficits and Anxiety-Like Behaviors in the D-Galactose-Induced Aging Mouse Model through Modulation of Oxidative Stress.Antioxidants (Basel, Switzerland) · 2021Article
- A Walnut Diet in Combination with Enriched Environment Improves Cognitive Function and Affects Lipid Metabolites in Brain and Liver of Aged NMRI Mice.Neuromolecular medicine · 2021Article
- Integration of lncRNA and mRNA profiles to reveal the protective effects ofInternational journal of molecular medicine · 2021Article
- Antioxidant activity of selenium-enriched Chrysomyia megacephala (Fabricius) larvae powder and its impact on intestinal microflora in D-galactose induced aging mice.BMC complementary medicine and therapies · 2020Article
- Oligosaccharide attenuates aging-related liver dysfunction by activating Nrf2 antioxidant signaling.Food science & nutrition · 2020Article
- Protective effect of walnut on d-galactose-induced aging mouse model.Food science & nutrition · 2019Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objective sAccumulating evidence has suggested that oxidative stress and apoptosis are involved in the aging process. d-galactose (gal) has been reported to cause symptoms of aging in mice, accompanied by liver and brain injuries. Our present work was to study the potential antioxidative and anti-apoptotic effects of walnut and to explore how these effects act on mice in a d-gal-induced aging model. MATERIALS AND
methodsAging mice were induced by subcutaneous injection of d-gal (200 mg kg
resultsThe kernel pellicles of walnut could not only improve the learning and memory ability, and the organ index, but also significantly decrease body weight and normalize the levels of activity of antioxidative enzymes in aging mice. Further, the walnut seed coat would protect damages of hippocampus and liver in aging mice. HIGHLIGHTS: In the current study, we investigated the effects of walnut kernels and walnut seed coats (WSCs) on d-galactose-induced aging mice. WSC was firstly found to have beneficial effects on d-gal-treated mouse's brain with learning and memory impairment, which probably through the underlying mechanism reduces oxidative damage and limits neuroinflammation. In addition, WSC had a protective effect on liver damage in d-galactose sensing mice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.