Evidence map›Paper›PMID 30918622›Full record

ArticleMolecular autism2019

The oxytocin receptor gene predicts brain activity during an emotion recognition task in autism.

Florina Uzefovsky, Richard A I Bethlehem, Simone Shamay-Tsoory, Amber Ruigrok, Rosemary Holt, Michael Spencer, Lindsay Chura, Varun Warrier, Bhismadev Chakrabarti, Ed Bullmore and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular autism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Roles of the Oxytocin Receptor (OXTR) in Human Diseases.International journal of molecular sciences · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Neuroimaging Markers of Risk and Pathways to Resilience in Autism Spectrum Disorder.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Florina Uzefovsky1Department of Psychology and Zlotowski Center for Neuroscience, Ben Gurion University of the Negev, 84105 Be'er Sheva, Israel.ORCID 0000-0003-4571-2514
Richard A I Bethlehem2Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, UK.
Simone Shamay-Tsoory3Department of Psychology, University of Haifa, Haifa, Israel.
Amber Ruigrok2Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, UK.
Rosemary Holt2Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, UK.
Michael Spencer2Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, UK.
Lindsay Chura2Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, UK.
Varun Warrier2Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, UK.
Bhismadev Chakrabarti4School of Psychology and Clinical Language Sciences, University of Reading, Reading, UK.
Ed Bullmore2Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, UK.
John Suckling2Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, UK.
Dorothea Floris2Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, UK.
Simon Baron-Cohen2Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, UK.
University of Cambridge · GBAmerican Academy of Child and Adolescent Psychiatry · USBen-Gurion University of the Negev · ILUniversity of Haifa · ILUniversity of Reading · GB

Funding

Medical Research Council G0701919Wellcome Trust
6 · The paper itself

Abstract

Background: Autism is a highly varied and heritable neurodevelopmental condition, and common variants explain approximately 50% of the genetic variance of autism. One of the genes implicated in autism is the oxytocin receptor ( Methods: Participants were adolescents (mean age = 14.7 ± 1.7) who were genotyped for single nucleotide polymorphisms (SNPs) within the Results: Two (rs2254298, rs53576) of the five Conclusions: This is one of the first studies to investigate

Indexed as

Facial RecognitionPolymorphism, Single NucleotideAdolescentAutistic DisorderBrainChildEmotionsFemaleGenotypeHumansMagnetic Resonance ImagingMaleReceptors, OxytocinOXTR protein, humanReceptors, OxytocinAutismfMRIImaging geneticsOxytocin receptorSupramarginal gyrus

Identifiers

PMID30918622
PMCPMC6419364
OpenAlexW2936520785

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.