Evidence map›Paper›PMID 30918597›Full record

ArticleWorld journal of gastrointestinal oncology2019

Near-infrared fluorescence guided esophageal reconstructive surgery: A systematic review.

Elke Van Daele, Yves Van Nieuwenhove, Wim Ceelen, Christian Vanhove, Bart P Braeckman, Anne Hoorens, Jurgen Van Limmen, Oswald Varin, Dirk Van de Putte, Wouter Willaert and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in World journal of gastrointestinal oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.

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  9. Indocyanine green fluorescence video-angiography for flap perfusion assessment in head and neck reconstruction: a prospective study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Elke Van DaeleDepartment of Gastrointestinal Surgery, Ghent University Hospital/Ghent University, Ghent B-9000, Belgium. elke.vandaele@uzgent.be.
Yves Van NieuwenhoveDepartment of Gastrointestinal Surgery, Ghent University Hospital/Ghent University, Ghent B-9000, Belgium.
Wim CeelenDepartment of Gastrointestinal Surgery, Ghent University Hospital/Ghent University, Ghent B-9000, Belgium.
Christian VanhoveDepartment of Electronics and information systems, Ghent University, Ghent B-9000, Belgium.
Bart P BraeckmanDepartment of Biology, Ghent University, Ghent B-9000, Belgium.
Anne HoorensDepartment of Pathology, Ghent University Hospital/Ghent University, Ghent B-9000, Belgium.
Jurgen Van LimmenDepartment of Anaesthesiology, Ghent University Hospital/ Ghent University, Ghent B-9000, Belgium.
Oswald VarinDepartment of Gastrointestinal Surgery, Ghent University Hospital/Ghent University, Ghent B-9000, Belgium.
Dirk Van de PutteDepartment of Gastrointestinal Surgery, Ghent University Hospital/Ghent University, Ghent B-9000, Belgium.
Wouter WillaertDepartment of Gastrointestinal Surgery, Ghent University Hospital/Ghent University, Ghent B-9000, Belgium.
Piet PattynDepartment of Gastrointestinal Surgery, Ghent University Hospital/Ghent University, Ghent B-9000, Belgium.
Ghent University · BEGhent University Hospital · BECreative Research Enterprises (United States) · USUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAfter an esophagectomy, the stomach is most commonly used to restore continuity of the upper gastrointestinal tract. These esophago-gastric anastomoses are prone to serious complications such as leakage associated with high morbidity and mortality. Graft perfusion is considered to be an important predictor for anastomotic integrity. Based on the current literature we believe Indocyanine green fluorescence angiography (ICGA) is an easy assessment tool for gastric tube (GT) perfusion, and it might predict anastomotic leakage (AL).

aimTo evaluate feasibility and effectiveness of ICGA in GT perfusion assessment and as a predictor of AL.

methodsThis study was designed according to the PRISMA guidelines and registered in the PROSPERO database. PubMed and EMBASE were independently searched by 2 reviewers for studies presenting data on intraoperative ICGA GT perfusion assessment during esophago-gastric reconstruction after esophagectomy. Relevant outcomes such as feasibility, complications, intraoperative surgical changes based on ICGA findings, quantification attempts, anatomical data and the impact of ICGA on postoperative anastomotic complications, were collected by 2 independent researchers. The quality of the included articles was assessed based on the Methodological Index for Non-Randomized Studies. The 19 included studies presented data on 1192 esophagectomy patients, in 758 patients ICGA was used perioperative to guide esophageal reconstruction.

resultsThe 19 included studies for qualitative analyses all described ICGA as a safe and easy method to evaluate gastric graft perfusion. AL occurred in 13.8% of the entire cohort, 10% in the ICG guided group and 20.6% in the control group (

conclusionICGA is a safe, feasible and promising method for perfusion assessment. The lower AL rate in the well perfused group suggest that a good fluorescent signal predicts a good outcome.

Indexed as

Anastomotic leakAngiographyEsophageal cancerEsophageal neoplasmsEsophagectomyFluorescenceIndocyanine greenNear-infrared spectroscopy

Identifiers

PMID30918597
PMCPMC6425328
OpenAlexW2921123879

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.