Evidence map›Paper›PMID 30918507›Full record

ArticleFrontiers in immunology2019

CpGs Induce Differentiation of Atlantic Salmon Mononuclear Phagocytes Into Cells With Dendritic Morphology and a Proinflammatory Transcriptional Profile but an Exhausted Allostimulatory Activity.

Dimitar B Iliev, Leidy Lagos, Hanna L Thim, Sven M Jørgensen, Aleksei Krasnov, Jorunn B Jørgensen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Why DoesFrontiers in immunology · 2022
    Review
  2. Nutritional immunomodulation of Atlantic salmon response toFrontiers in molecular biosciences · 2022
    Article
  3. Expression of DC-SIGN-like C-Type Lectin Receptors in Salmo salar.Developmental and comparative immunology · 2020
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Dimitar B IlievThe Norwegian College of Fishery Science, UiT The Arctic University of Norway, Tromsø, Norway.
Leidy LagosThe Norwegian College of Fishery Science, UiT The Arctic University of Norway, Tromsø, Norway.
Hanna L ThimThe Norwegian College of Fishery Science, UiT The Arctic University of Norway, Tromsø, Norway.
Sven M JørgensenNofima Marin AS, Oslo, Norway.
Aleksei KrasnovNofima Marin AS, Oslo, Norway.
Jorunn B JørgensenThe Norwegian College of Fishery Science, UiT The Arctic University of Norway, Tromsø, Norway.
UiT The Arctic University of Norway · NOFafo Foundation · NOInstitute of Molecular Biology · BGNofima · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to their ability to present foreign antigens and prime naïve T cells, macrophages, and dendritic cells (DCs) are referred to as professional antigen-presenting cells (APCs). Although activated macrophages may function as APCs, these cells are particularly effective at directly engaging pathogens through phagocytosis, and production of antimicrobial compounds. On the other hand, DCs possess superb antigen-presenting and costimulatory capacity and they are essential for commencement and regulation of adaptive immune responses. In

Indexed as

DendritesTranscriptomeAnimalsBiomarkersCell DifferentiationCells, CulturedGene Expression ProfilingInflammation MediatorsMononuclear Phagocyte SystemOligodeoxyribonucleotidesPhagocytosisSalmo salarBiomarkersCPG-oligonucleotideInflammation MediatorsOligodeoxyribonucleotidesantigen-presenting cellsAtlantic salmonCpG oligodeoxynucleotidesdendritic cellsmononuclear phagocytesteleosts

Identifiers

PMID30918507
PMCPMC6424866
OpenAlexW2922367771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.