Observational studyWorld journal of gastroenterology2019
Diffusion-weighted magnetic resonance imaging and micro-RNA in the diagnosis of hepatic fibrosis in chronic hepatitis C virus.
Observational study in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Value of intravoxel incoherent motion in detecting and staging liver fibrosis: A meta-analysis.World journal of gastroenterology · 2020Pooled it
- Predictive intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) parameters in the staging of fibrosis in hepatitis B patients.Polish journal of radiology · 2025Article
- Transient elastography and diffusion-weighted magnetic resonance imaging for assessment of liver fibrosis in children with chronic hepatitis C.World journal of virology · 2024Article
- Staging liver fibrosis with various diffusion-weighted magnetic resonance imaging models.World journal of gastroenterology · 2024Article
- [Expert consensus on MRI diagnosis of liver fibrosis in chronic hepatitis B (version 2023)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2023Article
- Role of noncoding RNAs in liver fibrosis.World journal of gastroenterology · 2023Review
- Article
- Sequential HBV treatment with tenofovir alafenamide for patients with chronic hepatitis B: week 96 results from a real-world, multicenter cohort study.Hepatology international · 2022Article
- A novel radiomics-platelet nomogram for the prediction of gastroesophageal varices needing treatment in cirrhotic patients.Hepatology international · 2021Article
- Noncoding RNAs as Promising Diagnostic Biomarkers and Therapeutic Targets in Intestinal Fibrosis of Crohn's Disease: The Path From Bench to Bedside.Inflammatory bowel diseases · 2021Review
- Hsa-circRNA-103809 Promotes Hepatocellular Carcinoma Development via MicroRNA-1270/PLAG1 Like Zinc Finger 2 Axis.Digestive diseases and sciences · 2021Article
- The longitudinal outcomes of applying non-selective beta-blockers in portal hypertension: real-world multicenter study.Hepatology international · 2021Article
- Identification of METTL3 as an Adverse Prognostic Biomarker in Hepatocellular Carcinoma.Digestive diseases and sciences · 2021Article
- Attenuation Imaging with Ultrasound as a Novel Evaluation Method for Liver Steatosis.Journal of clinical medicine · 2021Article
- Dual-Energy Computed Tomography of the Liver: Uses in Clinical Practices and Applications.Diagnostics (Basel, Switzerland) · 2021Review
- Therapeutic effect of adenosylmethionine on viral hepatitis and related factors inducing diseas.American journal of translational research · 2021Article
- Longitudinal decrease in platelet counts as a surrogate marker of liver fibrosis.World journal of gastroenterology · 2020Article
- Higher frequency of hepatic steatosis at CT among COVID-19-positive patients.Abdominal radiology (New York) · 2020Article
- Celecoxib attenuates hepatocyte apoptosis by inhibiting endoplasmic reticulum stress in thioacetamide-induced cirrhotic rats.World journal of gastroenterology · 2020Article
- Hepatic microenvironment underlies fibrosis in chronic hepatitis B patients.World journal of gastroenterology · 2020Article
Corrections and comments
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiffusion-weighted magnetic resonance imaging has shown promise in the detection and quantification of hepatic fibrosis. In addition, the liver has numerous endogenous micro-RNAs (miRs) that play important roles in the regulation of biological processes such as cell proliferation and hepatic fibrosis.
aimTo assess diffusion-weighted magnetic resonance imaging and miRs in diagnosing and staging hepatic fibrosis in patients with chronic hepatitis C.
methodsThis prospective study included 208 patients and 82 age- and sex-matched controls who underwent diffusion-weighted magnetic resonance imaging of the abdomen, miR profiling, and liver biopsy. Pathological scoring was classified according to the METAVIR scoring system. The apparent diffusion coefficient (ADC) and miR were calculated and correlated with pathological scoring.
resultsThe ADC value decreased significantly with the progression of fibrosis, from controls (F0) to patients with early fibrosis (F1 and F2) to those with late fibrosis (F3 and F4) (median 1.92, 1.53, and 1.25 × 10
conclusionCombining ADC and miRs offers an alternative surrogate non-invasive diagnostic tool for diagnosing and staging hepatic fibrosis in patients with chronic hepatitis C.
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