Evidence map›Paper›PMID 30918198›Full record

ArticleInternal medicine (Tokyo, Japan)2019

Bucillamine-induced Pneumonitis in a Patient with Rheumatoid Arthritis-associated Interstitial Pneumonia: A Case Report and Review of the Literature.

Atsuki Fukada, Mikio Toyoshima, Tsuyoshi Nozue, Takafumi Suda

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Redefining the role of the thiol-based agentRSC medicinal chemistry · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Atsuki FukadaDepartment of Respiratory Medicine, Hamamatsu Rosai Hospital, Japan.
Mikio ToyoshimaDepartment of Respiratory Medicine, Hamamatsu Rosai Hospital, Japan.
Tsuyoshi NozueDepartment of Respiratory Medicine, Hamamatsu Rosai Hospital, Japan.
Takafumi SudaSecond Department of Internal Medicine, Hamamatsu University School of Medicine, Japan.
Hamamatsu Rosai Hospital · JPHamamatsu University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An 81-year-old woman with rheumatoid arthritis (RA) who had been treated with bucillamine presented with dyspnea. Computed tomography of the chest showed ground-glass opacities and consolidations in both lungs and honeycombing in both basal lung areas. An elevation of the serum Krebs von den Lungen-6 level and hypoxemia were seen. Lymphocytosis with a decreased CD4/CD8 ratio was seen in the bronchoalveolar lavage fluid. A transbronchial lung biopsy specimen showed organizing pneumonia. Based on a diagnosis of bucillamine-induced pneumonitis (BIP) with RA-associated pre-existing interstitial pneumonia, she was successfully treated with the cessation of bucillamine and systemic corticosteroid therapy. The risk factors and prognosis of BIP are discussed.

Indexed as

Aged, 80 and overAnti-Inflammatory Agents, Non-SteroidalArthritis, RheumatoidBronchoalveolar Lavage FluidCysteineDyspneaFemaleHumansHypoxiaLungLung Diseases, InterstitialLymphocyte CountPneumoniaTomography, X-Ray ComputedAnti-Inflammatory Agents, Non-SteroidalbucillamineCysteinebucillamine-induced pneumonitisinterstitial pneumoniamethotrexaterheumatoid arthritis

Identifiers

PMID30918198
PMCPMC6709319
OpenAlexW4245489567

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.