Evidence map›Paper›PMID 30918164›Full record

ArticleJournal of atherosclerosis and thrombosis2019

Aortic Plaque Distribution, and Association between Aortic Plaque and Atherosclerotic Risk Factors: An Aortic Angioscopy Study.

Keisuke Kojima, Shigeki Kimura, Kazuto Hayasaka, Masafumi Mizusawa, Toru Misawa, Yosuke Yamakami, Yuichiro Sagawa, Hirofumi Ohtani, Keiichi Hishikari, Tomoyo Sugiyama and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of atherosclerosis and thrombosis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Keisuke KojimaCardiovascular Center, Yokosuka Kyosai Hospital.
Shigeki KimuraCardiovascular Center, Yokosuka Kyosai Hospital.
Kazuto HayasakaCardiovascular Center, Yokosuka Kyosai Hospital.
Masafumi MizusawaCardiovascular Center, Yokosuka Kyosai Hospital.
Toru MisawaCardiovascular Center, Yokosuka Kyosai Hospital.
Yosuke YamakamiCardiovascular Center, Yokosuka Kyosai Hospital.
Yuichiro SagawaCardiovascular Center, Yokosuka Kyosai Hospital.
Hirofumi OhtaniCardiovascular Center, Yokosuka Kyosai Hospital.
Keiichi HishikariCardiovascular Center, Yokosuka Kyosai Hospital.
Tomoyo SugiyamaCardiovascular Center, Yokosuka Kyosai Hospital.
Hiroyuki HikitaCardiovascular Center, Yokosuka Kyosai Hospital.
Atsushi TakahashiCardiovascular Center, Yokosuka Kyosai Hospital.
Yokosuka Kyosai Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimKnowledge of subclinical plaque morphology and plaque distribution in the aorta in vivo remains unclear. This study aimed to increase the body of knowledge in this area.

methodsWe enrolled 37 consecutive patients with stable angina pectoris patients who underwent non-obstructive angioscopy for both the coronary artery and aorta immediately after percutaneous coronary intervention. We evaluated the presence of aortic plaques and the distribution of plaque instability. Patients were allocated into two groups according to the number of vulnerable plaques in whole aorta (a low [0-11] and high [≥ 12] group). We evaluated the relationships between the two groups in terms of cardiovascular risk factors.

resultsAortic plaques were identified using non-obstructive angioscopy in all patients, and the greatest number of plaques was found at the infrarenal abdominal aorta (IAA) (the aortic arch, the descending thoracic aorta, the suprarenal abdominal aorta, the IAA, and common iliac artery; 65%, 76%, 65%, 95%, and 49%, respectively; p<0.001). The maximum yellow grade, and the number of intense yellow plaques, ruptured plaques, and thrombi were highest at the IAA (p<0.001). The prevalence of diabetes mellitus and peripheral arterial disease was higher in the high vulnerable plaque group (83.3% vs. 40.0%, p=0.010, 50.0% vs. 8.0%, p=0.005, respectively).

conclusionsAortic atherosclerosis was the most severe at the IAA, and aortic plaque vulnerability and distribution were associated with the prevalence of diabetes mellitus and peripheral artery disease in patients with stable angina pectoris. Non-obstructive angioscopy may identify patients at high risk of future aortic events.

Indexed as

AgedAngioscopyAortaAtherosclerosisFemaleFollow-Up StudiesHumansMalePlaque, AtheroscleroticPrognosisRetrospective StudiesRisk FactorsAortic angioscopyAortic plaque distributionAtheromatous plaqueAtherosclerotic risk factorsPlaque morphology

Identifiers

PMID30918164
PMCPMC6845689
OpenAlexW2922606397

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.